Results 81 to 90 of about 55,639 (278)

Impact of Sequential Ramucirumab Plus Docetaxel After PD‐1 Inhibitors on Anti‐PD‐1 Antibody‐Bound T‐Cell Dynamics and Clinical Outcomes

Cancer Science, EarlyView.
Ramucirumab (RAM) plus docetaxel (DOC) after PD‐1 inhibitors showed clinical activity, with responders exhibiting maintained anti–PD‐1 (IgG4+)‐bound CD8+ T cells and decreased IgG4+ Tregs. A sequential strategy of administering RAM plus DOC during persistent anti–PD‐1 antibody binding may be beneficial in patients with advanced non‐small cell lung ...
Kinnosuke Matsumoto, Yujiro Naito, Takayuki Shiroyama, Motohiro Tamiya, Kazumi Nishino, Akihiro Tamiya, Kyoichi Okishio, Yuhei Kinehara, Tomoki Kuge, Masahide Mori, Shingo Satoh, Hidekazu Suzuki, Satoshi Tetsumoto, Toshie Niki, Yasuhiko Suga, Akio Osa, Toshiyuki Minami, Shohei Koyama, Yoshito Takeda, Nobuyuki Takakura, Atsushi Kumanogoh   +20 more
wiley   +1 more source

Comparison of Piezoelectric and High‐Speed Drills for Frontal Beak Osteotomy in Endoscopic Sinus Surgery—Exploratory Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Frontal beak reduction is a critical and challenging step in endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). Traditional high‐speed drills can risk thermal injury and soft tissue trauma, whereas piezoelectric surgery uses ultrasonic vibrations for selective bone cutting and may improve surgical precision.
Łukasz Skrzypiec, Kornel Szczygielski, Agnieszka Brociek‐Piłczyńska, Dariusz Jurkiewicz, Marta Aleksandra Kwiatkowska   +4 more
wiley   +1 more source

Evaluation of Hematologic Markers in Hypertensive and Non-hypertensive Epistaxis Patients [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy
Objective: The objective of the study is to investigate the development of epistaxis and its relationship with hypertension, as well as inflammatory parameters such as the neutrophil-lymphocyte ratio (NLR), the pan-immune inflammation value (PIV), the ...
Yeşim Yüksel, Rezarta Taga Senirli, Nuray Ensari, Cihan Bedel, Fatih Selvi, Ökkeş Zortuk, Mustafa Korkut   +6 more
doaj   +1 more source

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Outpatient management of pediatric epistaxis: A cost analysis and clinical model

Laryngoscope Investigative Otolaryngology
Objective(s) Pediatric epistaxis is a common, often non‐operative condition encountered by Otolaryngologists. The present study seeks to (1) describe our outcomes of epistaxis management, (2) estimate the associated healthcare burden, and (3) propose a ...
Joshua A. Lee, Christopher Puchi, Kathleen R. Billings, Jennifer M. Lavin, Inbal Hazkani, Carole Glennon, Dana M. Thompson, John Maddalozzo   +7 more
doaj   +1 more source

Case Report: Massive epistaxis from juvenile angiofibroma in an adolescent with severe haemophilia A [version 1; peer review: 3 approved]

F1000Research, 2019
Epistaxis may be profuse in individuals with normal bleeding parameters, but in an individual with haemophilia, it may be life-threatening. It is even more dangerous when epistaxis is caused by an undetected concomitant juvenile angiofibroma, and only ...
Jose Florencio F. Lapeña, Olivia Agnes D. Mejia   +1 more
doaj   +1 more source

Imperial Epistaxis and Edema: Insights into the Death of the Roman Emperor Hadrian

, 2021
Perry Hammond, Jonathan R. Mark, Rebecca R. Benefiel   +2 more
openalex   +1 more source

Frequency of epistaxis and telangiectasia in patients with hereditary hemorrhagic telangiectasia (HHT) in comparison with the general population: Curaçao diagnostic criteria revisited [PDF]

, 2023
Jamie McDonald, Jenna Kornish, David A. Stevenson, Andrea Hanson‐Kahn, Heather Balch, John James, Hetanshi Naik, Kevin J. Whitehead   +7 more
openalex   +1 more source

Efficacy of TIMOLOL nasal spray as a treatment for epistaxis in hereditary hemorrhagic telangiectasia. A double-blind, randomized, placebo-controlled trial

Scientific Reports, 2019
Hereditary hemorrhagic telangiectasia is a rare vascular genetic disease. Epistaxis is the most frequent and disabling manifestation, and timolol appears to be a new therapeutic option as non-selective beta-blockers have in vitro and in vivo anti ...
S. Dupuis-Girod, Vincent Pitiot, C. Bergerot, A. Fargeton, M. Beaudoin, E. Decullier, V. Bréant, Bettina Colombet, P. Philouze, F. Faure, Jean-Charles Letievant   +10 more
semanticscholar   +1 more source

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

Equine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg, K. Drozdzewska, K. Landmann, A. Voß, K. Kunze, D. Rutenberg, A. D. Gruber, H. Gehlen   +7 more
wiley   +1 more source