Results 201 to 210 of about 58,378 (265)

ZC3H13‐mediated m6A stabilization of CCND1 promotes malignant progression and is associated with poor anti‐PD‐1 response in HNSCC

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
ZC3H13 promotes HNSCC progression and anti‐PD‐1 resistance by enhancing IGF2BP1‐mediated stabilization of CCND1 mRNA in an m6A‐dependent manner. Targeting ZC3H13 suppresses oral tumorigenesis and improves response to PD‐1 blockade. Abstract Background Resistance to immune checkpoint blockade substantially limits its clinical efficacy in head and neck ...
Wenqing Chen, Yun Li, Shuang Chen, Caihua Zhang, Zhi Liu, Kai Sun, Yingyi Li, Chunlong Yang, Wenbin Lei, Kang Li   +9 more
wiley   +1 more source

An Update on the Use of Artificial Intelligence in Digital Pathology for Oral Epithelial Dysplasia Research. [PDF]

Head Neck Pathol
Alajaji SA, Khoury ZH, Jessri M, Sciubba JJ, Sultan AS.   +4 more
europepmc   +1 more source

Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland

Head &Neck, Volume 48, Issue 8, Page 2231-2237, August 2026.
ABSTRACT Background Oral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED. Methods Patients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included.
Katariina Leino, Hanna K. Laine, Ville Kinnula, Jaana Rautava   +3 more
wiley   +1 more source

The Significance of Modified Histone H3 in Epithelial Dysplasia and Oral Cancer. [PDF]

Int Dent J
Tachaveeraphong W, Phattarataratip E.
europepmc   +1 more source

Melatonin and Lactation in Ruminants Dairy Animals: A Systematic Review and Meta‐Analysis of Preclinical Studies

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Melatonin is present in breast milk with a diurnal pattern, potentially supporting early circadian rhythm development. This systematic review and meta‐analysis aimed to evaluate the effects of exogenous melatonin supplementation, compared with no treatment or placebo, on milk yield, milk composition, somatic cell count ...
Reza Sattarpour, Maryam Noori, Parvaneh Sadeghimoghadam, Nasim Sattarpour, Parvin Bastani   +4 more
wiley   +1 more source

A fully automated and explainable algorithm for predicting malignant transformation in oral epithelial dysplasia. [PDF]

NPJ Precis Oncol
Shephard AJ, Bashir RMS, Mahmood H, Jahanifar M, Minhas F, Raza SEA, McCombe KD, Craig SG, James J, Brooks J, Nankivell P, Mehanna H, Khurram SA, Rajpoot NM.   +13 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2599-2622, August 2026.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Histomorphometric Analysis of Oral Squamous Cell Carcinoma, Apparently Normal Adjacent Mucosa and Epithelial Dysplasia. [PDF]

Indian J Otolaryngol Head Neck Surg
Mirhashemi M, Saghravanian N, Ghazi N, Abdoljavadi A.   +3 more
europepmc   +1 more source

Bone Marrow Stem Cell Exosomes Protect Lung Cells from Oxygen Damage by Regulating miR‐23a‐3p/Slc7a2 Pathway

The Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
Exosomal miR‐23a‐3p from BMSCs directly targets Slc7a2 mRNA. By repressing Slc7a2, miR‐23a‐3p suppresses hyperoxia‐triggered apoptosis, facilitates proliferation and reduces ROS production in AECIIs in vitro. The miR‐23a‐3p/Slc7a2 axis modulates numerous biochemical markers in AECII supernatant and neonatal rat serum under hyperoxia (P 〈 0.05 ...
Qifei He, Huaiwu Zheng, Junhao Xiong, Wei Yang   +3 more
wiley   +1 more source