Results 221 to 230 of about 244,147 (243)

Phosphate Toxicity and Epithelial to Mesenchymal Transition

2022
The underlying role of inadequate or excess intake of phosphate is evident in disease states, including metabolic, skeletal, cardiac, kidney and various cancers. Elevated phosphate levels can induce epithelial to mesenchymal transition (EMT) and cell death.
Eric, Lewis, Faith, Seltun, Mohammed S, Razzaque, Ping, He   +3 more
openaire   +2 more sources

Cadherins and Epithelial-to-Mesenchymal Transition

2013
Epithelial-mesenchymal transition (EMT) is a process whereby epithelial cells are transcriptionally reprogrammed, resulting in decreased adhesion and enhanced migration or invasion. EMT occurs during different stages of embryonic development, including gastrulation and neural crest cell delamination, and is induced by a panel of specific transcription ...
Alexander, Gheldof, Geert, Berx
openaire   +2 more sources

The crucial role of ZEB2: From development to epithelial‐to‐mesenchymal transition and cancer complexity

Journal of Cellular Physiology, 2019
Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved process during which mature and adherent epithelial‐like state is converted into
Masoumeh Fardi, M. Alivand, B. Baradaran, Majid farshdousti hagh, Saeed Solali   +4 more
semanticscholar   +1 more source

Epithelial-to-Mesenchymal Transition in Renal Neoplasms

Advances in Anatomic Pathology, 2014
Epithelial-to-mesenchymal transition (EMT) describes a phenotypical change induced in epithelial cells that lose their cell-cell basement membrane contacts and their structural polarity to become spindle-shaped and morphologically similar to mesenchymal/myofibroblast cell.
Huiying, He, Cristina, Magi-Galluzzi
openaire   +2 more sources

Epithelial to Mesenchymal Transition

Critical Care Medicine, 2012
Anil K, Sharma, Rolf D, Hubmayr
  +5 more sources

Role of Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease

Journal of Crohn's & Colitis, 2018
Intestinal fibrosis is an inevitable complication in patients with inflammatory bowel disease [IBD], occurring in its two major clinical manifestations: ulcerative colitis and Crohn's disease. Fibrosis represents the final outcome of the host reaction to
S. Lovisa, G. Genovese, S. Danese
semanticscholar   +1 more source

Evolutionary fingerprints of epithelial-to-mesenchymal transition

Nature
Mesenchymal plasticity has been extensively described in advanced epithelial cancers; however, its functional role in malignant progression is controversial1-5. The function of epithelial-to-mesenchymal transition (EMT) and cell plasticity in tumour heterogeneity and clonal evolution is poorly understood.
Luigi Perelli, Li Zhang, Sarah Mangiameli, Francesca Giannese, Krishnan K. Mahadevan, Fuduan Peng, Francesca Citron, Hania Khan, Courtney Le, Enrico Gurreri, Federica Carbone, Andrew J. C. Russell, Melinda Soeung, Truong Nguyen Anh Lam, Sebastian Lundgren, Sujay Marisetty, Cihui Zhu, Desiree Catania, Alaa M. T. Mohamed, Ningping Feng, Jithesh Jose Augustine, Alessandro Sgambato, Giampaolo Tortora, Giulio F. Draetta, Giovanni Tonon, Andrew Futreal, Virginia Giuliani, Alessandro Carugo, Andrea Viale, Michael P. Kim, Timothy P. Heffernan, Linghua Wang, Raghu Kalluri, Davide Cittaro, Fei Chen, Giannicola Genovese   +35 more
openaire   +2 more sources

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

Nature Cell Biology, 2008
P. A. Gregory, A. Bert, Emily Paterson, S. Barry, A. Tsykin, G. Farshid, M. Vadas, Y. Khew-Goodall, G. Goodall   +8 more
semanticscholar   +1 more source

Epithelial to Mesenchymal Transition

2022
Annamarie C. Dalton, Philip H. Howe
openaire   +1 more source

BMP-7 counteracts TGF-β1–induced epithelial-to-mesenchymal transition and reverses chronic renal injury

Nature Medicine, 2003
M. Zeisberg, J. Hanai, H. Sugimoto, T. Mammoto, D. Charytan, F. Strutz, R. Kalluri   +6 more
semanticscholar   +1 more source