Results 91 to 100 of about 36,944 (259)

Variant WWTR1 gene fusions in epithelioid hemangioendothelioma—A genetic subset associated with cardiac involvement

Genes, Chromosomes and Cancer, 2020
The genetic hallmark of epithelioid hemangioendothelioma (EHE) is a recurrent WWTR1‐CAMTA1 fusion, which is present in most cases bearing a conventional histology.
A. Suurmeijer, B. Dickson, D. Swanson, Yun‐Shao Sung, Lei Zhang, C. Antonescu   +5 more
semanticscholar   +1 more source

Clinical and biological factors associated with response to immune checkpoint inhibitors in advanced sarcomas: IMPRESARC, a French retrospective multicenter cohort study

Cancer, Volume 131, Issue 18, 15 September 2025.
Abstract Background Immune checkpoint inhibitors (ICIs) in unselected sarcomas yield limited response rates and tumor control. Long‐term responders have however been reported, suggesting a critical challenge in refining patient selection, by identifying reliable predictive factors for response. Methods The authors conducted a multicenter, retrospective
Mina Fazel, Romain Varnier, Hélène Vanacker, Nicolas Penel, Sarah Watson, Benjamin Verret, Thibaud Valentin, Emmanuelle Bompas, Waisse Waissi, Alexandra Meurgey, Françoise Ducimetière, Jean‐Yves Blay, Armelle Dufresne, Mehdi Brahmi   +13 more
wiley   +1 more source

Hemangioendotelioma epitelial: um tumor raro com apresentação atípica

Galicia Clínica, 2016
Epithelioid Hemangioendothelioma is a rare neoplasia, and has its origin in the vascular endothelium. It may grow in several organs and tissues. There is not any approved therapeutic scheme and the prognosis is unpredictable.
Madalena Reis, Alcina Tavares, Luís Ferreira, Lina De Carvalho   +3 more
doaj   +1 more source

Activity of sirolimus in patients with progressive epithelioid hemangioendothelioma: A case‐series analysis within the Italian Rare Cancer Network

Cancer, 2020
The objective of this study was to report on a retrospective series of patients with epithelioid hemangioendothelioma (EHE) who received treatment with sirolimus within the Italian Rare Cancer Network.
S. Stacchiotti, N. Simeone, S. Lo Vullo, G. Baldi, A. Brunello, B. Vincenzi, E. Palassini, G. Dagrada, P. Collini, C. Morosi, F. Greco, M. Sbaraglia, A. D. Dei Tos, L. Mariani, A. Frezza, P. Casali   +15 more
semanticscholar   +1 more source

YAP1::KMT2A‐Rearranged Sarcoma: Report of a New Case With Unusual Morphology and Immunohistochemical Features

Genes, Chromosomes and Cancer, Volume 64, Issue 7, July 2025.
ABSTRACT Recurrent KMT2A and YAP1 related fusions have recently been reported in various mesenchymal neoplasms of different histogenesis. First, YAP1::KMT2A fusions have been described in a subset of MUC4‐negative sclerosing epithelioid fibrosarcomas (SEF), while VIM::KMT2A fusions in a handful of cases associated with an undifferentiated spindle cell ...
Caterina Fumagalli, Ruth Orellana, Sílvia Bagué, Malena Ferré, Allan Gonzalez, Lluis Catasús, Jaume Llauger, Ana Peiró, Paul Zamora Alarcón, Katarina Majercakova, Raúl Terés, Marie Karanian‐Philippe, Franck Tirode, Cristina R. Antonescu   +13 more
wiley   +1 more source

Low-Grade Uterine Epithelioid Hemangioendothelioma Presented as a Submucosal Leiomyoma during Labor

Case Reports in Pathology, 2013
With the exception of leiomyomas, soft tissue tumors of the uterine corpus are not common. This is particularly true for vascular neoplasms, with the epithelioid hemangioendothelioma being a curiosity; not more than twenty-two cases of malignant ...
Anastasios V. Koutsopoulos, Efthimios Sivridis, Panagiotis Tsikouras, Vasileios Liberis, Georgia Karpathiou, Alexandra Giatromanolaki   +5 more
doaj   +1 more source

Hepatic Epithelioid Hemangioendothelioma

Вестник рентгенологии и радиологии, 2020
The paper gives a clinical example of diagnosing hepatic epithelioid hemangioendothelioma. With allowance made for that the tumor occurs rarely (less than 1% of cases of all vascular tumors), the authors provide the clinical example to demonstrate the ...
I. Z. Korobkova, D. A. Dremin, S. M. Kakalov, I. V. Kirsan', I. S. Skrynnikov, A. A. Ugrimov, M. N. Sorokin   +6 more
doaj   +1 more source

Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA–RNA Comprehensive Genomic Profiling Test

Cancer Science, Volume 116, Issue 7, Page 1984-1995, July 2025.
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe, Miho Ogawa, Aya Shinozaki‐Ushiku, Shuichi Tsutsumi, Kenji Tatsuno, Hiroyuki Aburatani, Hidenori Kage, Katsutoshi Oda   +7 more
wiley   +1 more source

A Cutaneous Vascular Neoplasm With an EWSR1‐NFATC2 Translocation—Contributing to the Spectrum of Vascular Lesions Characterized by NFATC‐Related Fusions

Journal of Cutaneous Pathology, Volume 52, Issue 6, Page 410-413, June 2025.
ABSTRACT Recently, a distinct subgroup of vascular neoplasms has been identified, characterized by NFATC‐related fusions. Although existing literature is limited, these lesions histologically show a variable appearance with a tendency for local recurrence but not distant spread.
B. Schurink, A. M. van Huizen, C. D. Savci‐Heijink, E.‐J. Kooi   +3 more
wiley   +1 more source

Metastatic Hepatic Epithelioid Hemangioendothelioma Treated with Olaratumab: A Falling Star Rising?

Therapeutics and Clinical Risk Management, 2020
Anastasios Kyriazoglou, 1 Konstantinos Koutsoukos, 1 Flora Zagouri, 1 Michalis Liontos, 1 Efthimios Dimitriadis, 2 Dina Tiniakos, 3, 4 Meletios Athanasios Dimopoulos 1 1Department of Clinical Therapeutics, General Hospital Alexandra, Athens, Greece ...
Kyriazoglou A, Koutsoukos K, Zagouri F, Liontos M, Dimitriadis E, Tiniakos D, Dimopoulos MA   +6 more
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