Results 21 to 30 of about 36,944 (259)

Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma.

Clinical Cancer Research, 2023
PURPOSE Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma caused by the WWTR1(TAZ)-CAMTA1 (TC) gene fusion. This fusion gene has been observed in almost all reported EHE cases and functions as a constitutively activated TAZ.
C. Seavey, Andrea Hallett, Shuo Li, Kepeng Che, A. Pobbati, Shuang Ma, Ashley Burtscher, Ryan Kanai, John M. Lamar, B. Rubin   +9 more
semanticscholar   +1 more source

CT appearances and classification of hepatic epithelioid hemangioendothelioma

Insights into Imaging, 2023
Background Hepatic epithelioid hemangioendothelioma (HEH) is extremely rare, and CT features have never been analyzed in a large group of patients. Methods A retrospective study was designed to review the contrast-enhanced CT images of HEH patients ...
H. Tan, Ruiquan Zhou, H. Yu, Feng Teng, S. Si, Liguo Liu, Shiwei Yang, Dongdong Han, Xiaolei Liu   +8 more
semanticscholar   +1 more source

Hepatic epithelioid hemangioendothelioma—a single-institution experience with 51 cases

Frontiers in Oncology, 2023
Objectives The aim of the present study was to describe the experience at a single institution in the management of hepatic epithelioid hemangioendothelioma (HEHE). Methods We included 51 patients with histologically confirmed HEHE. We performed log-rank
Lei Feng, Manjie Li, Zhuo Huang, Mingqing Xu   +3 more
semanticscholar   +1 more source

Successful chemotherapy with continuous immunotherapy for primary pulmonary endovascular epithelioid hemangioendothelioma: A case report

Medicine, 2023
Rationale: Epithelioid hemangioendothelioma (EHE) is a rare, low to moderate-grade malignancy, even less in pulmonary endovascular neoplasm. Patients with pulmonary EHE have no optimal treatment, resulting in poor prognoses. Patient concerns: We reported
W. Guo, Daibing Zhou, Hou-quan Huang, Hai-Ming Chen, Xiao-feng Wu, Xin Yang, Huiling Ye, C. Hong   +7 more
semanticscholar   +1 more source

Anteroposterior Combined Surgery of a Rare Massive Epithelioid Hemangioendothelioma at the Cervicothoracic Junction

Cureus, 2023
Epithelioid hemangioendothelioma is a rare mesenchymal tumor of vascular endothelial origin. Non-soft tissue epithelioid hemangioendothelioma can also be seen in different organs.
H. S. Cine, Ece Uysal, Salim Şenturk, Gülnihal Ay, B. Caner   +4 more
semanticscholar   +1 more source

Pleural Epithelioid Hemangioendothelioma (EHE): A Case Report

Cureus, 2023
Pleural epithelioid hemangioendothelioma (EHE) is a rare malignancy of vascular origin. It can affect various organs; pleural involvement is rare and lack of suspicion leads to delay in diagnosis.
V. Pathak, Christopher A Walker
semanticscholar   +1 more source

Case report: Surgical treatment of a primary giant epithelioid hemangioendothelioma of the spine with total en-bloc spondylectomy

Frontiers in Oncology, 2023
Background Epithelioid hemangioendothelioma (EHE) is an extremely uncommon malignant neoplasm that originates from vascular endothelial or pre-endothelial cells. In this report, we present the case of patient who was diagnosed with a primary giant EHE of
Wanbao Ge, Yuan-ming Qu, Ting-ting Hou, Jiayin Zhang, Qiuju Li, Lili Yang, Lanqing Cao, Jindong Li, Shanyong Zhang   +8 more
semanticscholar   +1 more source

An extremely rare case of pulmonary epithelioid hemangioendothelioma

Thoracic Cancer, 2023
Epithelioid emangioendothelioma (EHE) is a rare tumor originating from vascular endothelial cells, which belongs to malignant vascular tumors with low to moderate differentiation and potential metastatic ability and its incidence rate is less than one in
X. Chen, Yun Wang, G. Che, Cheng Shen
semanticscholar   +1 more source

Hepatic epithelioid hemangioendothelioma: Dilemma and challenges in the preoperative diagnosis

World Journal of Gastroenterology, 2016
Hai‐Jie Hu, Yanwen Jin, Qiuyang Jing, Anuj Shrestha, Nan-Sheng Cheng, Fu‐Yu Li   +5 more
openalex   +4 more sources

WWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis

Genes & Development, 2021
Here, Seavey et al. developed a conditional epithelioid hemangioendothelioma (EHE) mouse model whereby Wwtr1-Camta1 is controlled by the endogenous transcriptional regulators upon Cre activation by using an approach to target the Wwtr1-Camta1 gene fusion
C. Seavey, A. Pobbati, Andrea Hallett, Shuang-ping Ma, J. Reynolds, Ryan Kanai, John M. Lamar, B. Rubin   +7 more
semanticscholar   +1 more source