Results 131 to 140 of about 258,245 (301)
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang +7 more
wiley +1 more source
Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu +3 more
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To investigate, for the first time, whether an unconjugated VEGF‐A antisense oligonucleotide (ASO) can inhibit corneal neovascularisation and improve graft survival in a murine high‐risk corneal transplantation model. Methods A suture‐induced corneal neovascularisation model was established in BALB/c mice, followed by high‐risk ...
Wei Zhang +5 more
wiley +1 more source
Cell Proliferation, EarlyView.During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu +5 more
wiley +1 more source
Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source
Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou +5 more
wiley +1 more source
Equine eyelid reconstruction by semi‐circular skin flap blepharoplasty
Equine Veterinary Education, EarlyView.Summary Reconstructive surgeries of the equine eyelid carry significant challenges for the equine surgeon, due to the poorly mobile and tightly adhered facial skin in this species. Preservation of lid function is an essential surgical consideration in order to maintain protection of the globe and cornea and to provide ocular comfort to the case ...
V. J. Jordan, D. Leong, C. Hartley
wiley +1 more source
Apoptosis in the corneal epithelium.
Investigative ophthalmology & visual science, 1996 To determine the viability of corneal surface cells and to determine whether apoptosis is present in the corneal epithelium of the rabbit.The viability of epithelial surface cells was examined using a calcein-ethidium assay. In this two-color fluorescence assay, viable cells fluoresce green, and the nuclei of nonviable cells fluoresce red.
H, Ren, G, Wilson
openaire +1 more source
Darier disease—A review highlighting new insights from the Darier Disease International Task Force
Journal of the European Academy of Dermatology and Venereology, EarlyView.This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz +49 more
wiley +1 more source