Results 281 to 290 of about 489,867 (407)

Immune recognition of citrullinated epitopes

Immunology, 2016
Hai Nguyen, E. James
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Design and development of highly conserved, HLA-promiscuous T cell multiepitope vaccines against human visceral leishmaniasis. [PDF]

Front Immunol
Barreto AS, de Franca MNF, Dos Reis TLDS, Silva JABM, Dos Santos PL, de Oliveira FA, da Silva AM, Magalhaes LS, Secco DA, Andrade MAF, Porto LC, Rosa DS, Cavalcante RCM, Corrêa CB, Sidney J, Sette A, de Almeida RP, Palatnik-de-Sousa CB.   +17 more
europepmc   +1 more source

Identification and characterization of T helper epitopes in the nucleoprotein of influenza A virus. [PDF]

, 1989
Xiao‐Ming Gao, F Y Liew, J P Tite
openalex   +1 more source

Highly Conserved Protective Epitopes on Influenza B Viruses

Science, 2012
C. Dreyfus, N. S. Laursen, Ted H. J. Kwaks, D. Zuijdgeest, R. Khayat, D. Ekiert, J. H. Lee, Zoltan Metlagel, M. Bujny, M. Jongeneelen, R. van der Vlugt, M. Lamrani, Hans J. W. M. Korse, Eric Geelen, Ö. Şahin, M. Sieuwerts, J. Brakenhoff, R. Vogels, O. Li, L. Poon, M. Peiris, W. Koudstaal, A. Ward, I. Wilson, J. Goudsmit, R. Friesen   +25 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study. [PDF]

Vet Med Int
Abdul-Zahra HH, Khudhair YI, Al-Hraishawi HR.   +2 more
europepmc   +1 more source

The selectivity of Cathepsin D Suggests an Involvement of the Enzyme in the Generation of T-cell Epitopes

, 1989
Johannes M. van Noort, A C van der Drift
openalex   +1 more source

Monoclonal antibodies specific for Shigella flexneri lipopolysaccharides: clones binding to type IV, V, and VI antigens, group 3,4 antigen, and an epitope common to all Shigella flexneri and Shigella dysenteriae type 1 stains [PDF]

, 1987
Nils Carlin, Alf A. Lindberg
openalex   +1 more source

Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins

Proceedings of the National Academy of Sciences of the United States of America, 2015
Pietro Sormanni, F. Aprile, M. Vendruscolo   +2 more
semanticscholar   +1 more source