Results 301 to 310 of about 489,867 (407)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Computational Immunogenetic Analysis of Botulinum Toxin A Immunogenicity and HLA Gene Haplotypes: New Insights. [PDF]

Toxins (Basel)
Rahman E, Rao P, Ahmed M, Webb WR, Carruthers JDA.   +4 more
europepmc   +1 more source

Sequence of protective epitopes of streptococcal M proteins shared with cardiac sarcolemmal membranes. [PDF]

, 1987
Samantha Sargent, E H Beachey, Carlos Eduardo Pereira Corbett, James B. Dale   +3 more
openalex   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Harnessing computational immunology to design targeted subunit vaccines for infectious bursal disease in poultry. [PDF]

Front Bioinform
Oladipo EK, Adeyemo SF, Oshoneye AI, Akintola HB, Elegbede BI, Ayoomoba TU, Atilade DA, Adegboye OO, Ejikeme AE, Balogun CO, Aderibigbe KA, Popoola PO, Alabi VA, Irewolede BA, Ano-Edward GH, Ayeleso AO, Onyeaka H.   +16 more
europepmc   +1 more source

In vitro mutagenesis at a single residue introduces B and T cell epitopes into a class I HLA molecule. [PDF]

, 1987
Russell D. Salter, Carol Clayberger, C E Lomen, Alan M. Krensky, Peter Parham   +4 more
openalex   +1 more source

A high‐throughput shotgun mutagenesis approach to mapping B‐cell antibody epitopes

Immunology, 2014
E. Davidson, B. Doranz
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against <i>Brucella canis</i> Using a Reverse Vaccinology Approach. [PDF]

J Immunol Res
Arriagada V, Osorio A, Carrera-Naipil C, Villacis-Aguirre CA, Escobar C, Morales N, Villa D, Mardones L, Pérez D, Jara M, Molina RE, Ferrari Í, Azocar S, Gómez LA, Oñate ÁA.   +14 more
europepmc   +1 more source

Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

Circulation Research, 2011
Yury I. Miller, Soo-Ho Choi, Philipp Wiesner, Longhou Fang, R. Harkewicz, K. Hartvigsen, A. Boullier, A. Gonen, Cody J. Diehl, X. Que, Erica N. Montano, P. Shaw, S. Tsimikas, C. Binder, J. Witztum   +14 more
semanticscholar   +1 more source