Pan-vaccinomics strategy for developing a universal multi-epitope vaccine against endocarditis-related pathogens. [PDF]
Chao P+6 more
europepmc +1 more source
Computationally designed multi-epitope vaccine construct targeting the SARS-CoV-2 spike protein elicits robust immune responses in silico. [PDF]
Deepthi V+3 more
europepmc +1 more source
Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from <i>Loxosceles</i> spiders. [PDF]
Catalán A+10 more
europepmc +1 more source
A comprehensive strategy for the development of a multi-epitope vaccine targeting <i>Treponema pallidum</i>, utilizing heat shock proteins, encompassing the entire process from vaccine design to <i>in vitro</i> evaluation of immunogenicity. [PDF]
Jiang J+7 more
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
In silico construction of a multi-epitope vaccine (RGME-VAC/ATS-1) against the Rickettsia genus using immunoinformatics. [PDF]
Felice AG+10 more
europepmc +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Identification of B-cell epitopes of Indian Zika virus strains using immunoinformatics. [PDF]
Roy RR+5 more
europepmc +1 more source