Results 121 to 130 of about 72,828 (236)

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu   +13 more
wiley   +1 more source

Sex‐specific acceleration of Alzheimer's pathogenesis by chronic sleep‐deprivation

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep impairments likely contribute to Alzheimer's pathology, though specific contributions to disease progression are incompletely understood. We propose that autophagic impairment is associated with chronic sleep disruption and examine how sleep loss and stress influence disease development, including having impacts on ...
Darcy Wear   +5 more
wiley   +1 more source

Retrospective case series of high-density silicone oil (Oxane HD) in severe proliferative vitreorretinal retinal detachment patients

open access: yesInternational Journal of Retina and Vitreous
Background Describe complications and clinical outcomes of heavy silicone oil (HSO) Oxane HD® use as an alternative to overcome the challenges of performing vitrectomy to treat tractional and rhegmatogenous retinal detachments with proliferative ...
Ramon Antunes De Oliveira   +8 more
doaj   +1 more source

Effektmaaling af EPM [PDF]

open access: yes, 2008
This thesis is finalizing my Computer Science studies at the Roskilde University. Electronic Patient Records should contribute the Danish health sector with improved quality. I research on effectiveness of the Electronic Patient Medication module of EPR (in Danish EPM “Elektronisk Patient Medicinering”).
openaire  

APP‐mediated intracellular signaling rescues sleep impairment and blood–brain barrier leakage in Alzheimer's disease mouse model

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Amyloid beta peptide (Aβ) accumulation in the brain is an Alzheimer´s disease (AD) hallmark. Sleep disturbances hamper Aβ production and clearance, thereby exacerbating the Aβ burden. The mechanisms involved remain unclear. We reported that amyloid precursor protein (APP), the Aβ source, possesses intracellular signaling that ...
Clémentine Puech   +7 more
wiley   +1 more source

Further study on heredity of liquid aluminum modified by electric pulse [PDF]

open access: yesChina Foundry, 2011
The remarkable heredity of liquid aluminum modified by electric pulse (EP, EPM) has been uncovered. For better understanding from all aspects on the hereditary properties, the present research deals with the heredity destruction and the secondary EPM ...
Qi Jingang, Zhao Zuofu, Dai Shan
doaj  

The Rostral Ventrolateral Medulla Input to Central Amygdala Regulates Anxiety‐Like Behaviors in Mice for Chronic Light Exposure

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Jing et al. demonstrate that the CeA receives input from the RVLM in normal mice, and the chronic light exposure induced more pronounced elevated neuronal activity in the RVLM than the CeA. The enhanced excitatory input from the RVLM to CeA induced anxiety‐like behaviors in mice, revealing a novel circuit by which the RVLM regulates light‐related ...
Jia‐Ni Jing   +5 more
wiley   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

A Systematic Review on Functional Bioactive Compound Atractylone: Natural Source, Pharmacological Properties and Mechanisms Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Atractylone exhibits diverse pharmacological effects, including anticancer and neuroprotection. A systematic review was conducted following PRISMA guidelines to analyze Atractylone. This study explores Atractylone's sources, biosynthesis, and therapeutic potential.
Hamza Elhrech   +8 more
wiley   +1 more source

Caso grupo EPM - sostenibilidad financiera

open access: yes, 2023
Empresas Públicas de Medellín E. S. P. (EPM) es una empresa industrial del Estado de la cual el municipio de Medellín tiene el ciento por ciento de participación. A su vez, como dueña o accionista mayoritaria de diferentes compañías nacionales e internacionales, consolida su información financiera con la razón social Grupo EPM.
Quiceno Upegui, Tatiana   +1 more
openaire   +1 more source

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