American Journal of Hematology, Volume 100, Issue 5, Page 797-812, May 2025.ABSTRACT Patients with chronic inflammation are burdened with anemia of inflammation (AI), where inflammatory cytokines inhibit erythropoiesis, impede erythropoietin production, and limit iron availability by inducing the iron regulator hepcidin. High hepcidin hinders iron absorption and recycling, thereby worsening the impaired erythropoiesis by ...
Chia‐Yu Wang +16 more
wiley +1 more source
Dose reduction of epoetin-alpha in the prevention of chemotherapy-induced anaemia [PDF]
, 2018 Introduction: Anaemia during chemotherapy is often left untreated. Erythropoiesis-stimulating agents are frequently used to treat overt anaemia.
Biedermann, Beat +6 more
core
Switch from epoetin to darbepoetin alfa in hemodialysis: dose equivalence and hemoglobin stability
International Journal of Nephrology and Renovascular Disease, 2014 Javier Arrieta,1 Iñigo Moina,1 José Molina,2 Isabel Gallardo,3 María Luisa Muñiz,4 Carmen Robledo,5 Oscar García,5 Fernando Vidaur,6 Rosa Inés Muñoz,3 Izaskun Iribar,7 Román Aguirre,7 Antonio Maza8 ...
Arrieta J +11 more
doaj
Therapeutic efficacy of a biosimilar epoetin alfa in hemodialysis patients
Saudi Journal of Kidney Diseases and Transplantation, 2015 Anemia is a frequent complication in patients with chronic kidney disease. However, human recombinant erythropoietin (rHu-EPO) has revolutionized the management of anemia in chronically dialyzed patients.
Amel Harzallah +8 more
doaj +1 more source
Human choriogonadotropin and epoetin alfa in acute ischemic stroke patients (REGENESIS-LED trial). [PDF]
, 2014 IntroductionPreclinical studies suggest that growth factors in the early days after stroke improve final outcome. A prior study found three doses of human choriogonadotropin alfa followed by three doses of erythropoietin to be safe after stroke in humans.
Cramer, Steven C +2 more
core +1 more source
FERRIC CITRATE: AN IRON-BASED ORAL PHOSPHATE BINDER
Kidney Research and Clinical Practice, 2012 Patients with end-stage renal disease (ESRD) often experience secondary bone and mineral disorder requiring treatment with phosphate-binder (PB) medications, vitamin D sterols, and calcimimetics.
T. Christopher Bond +4 more
doaj +1 more source
Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines [PDF]
, 2017 Previously undiagnosed anaemia is common in elective orthopaedic surgical patients and is associated with increased likelihood of blood transfusion and increased perioperative morbidity and mortality. A standardized approach for the detection, evaluation,
Benoni, G. +12 more
core
Comparison of darbepoetin alfa dosed weekly (QW) vs. extended dosing schedule (EDS) in the treatment of anemia in patients receiving multicycle chemotherapy in a randomized, phase 2, open-label trial [PDF]
, 2010 BACKGROUND: Chemotherapy-induced anemia (CIA) is responsive to treatment with erythropoiesis-stimulating agents (ESAs) such as darbepoetin alfa. Administration of ESAs on a synchronous schedule with chemotherapy administration could benefit patients by ...
Amy Inamoto +7 more
core +2 more sources
Clinical Medicine Insights: Oncology, 2008 Introduction Anemia is the most frequent hematological disturbance in cancer patients, with prevalence between 30% and 90%, depending on the type of tumor, the antitumor treatment, and other factors (infection, malnutrition, bleeding, tumor infiltration ...
Pilar M Samper Ots +4 more
doaj +1 more source
Innovation and market dynamics in the EPO market [PDF]
In this paper we study the demand and supply of erythropoietin in four Nordic countries, using an econometric model based on discrete choice and a random utility model.
Sorisio, Enrico, Strøm, Steinar
core