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Detection of viruses in clinical samples by use of metagenomic sequencing and targeted sequence capture [PDF]

open access: yes, 2018
Buller, Richard   +5 more
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CHRONIC EPSTEIN-BARR VIRUS INFECTION

Annual Review of Medicine, 1987
The Epstein-Barr virus (EBV) has been associated with classic infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma, and B-cell lymphomas in primary and secondary immunodeficiency disease. The availability of specific serologic diagnosis of EBV, rather than dependence on heterophile antibody positivity, has broadened the scope of EBV ...
J F, Jones, S E, Straus
openaire   +3 more sources

Epstein-Barr Virus Infection

Pediatrics In Review, 1994
Introduction Virtually all humans become infected with Epstein-Barr virus (EBV). The vast majority of these infections are inapparent, occur early in life, and are associated with lifelong latent infection and persistent shedding of virus. Epidemiology The prevalence of antibody to EBV has been determined in
W A, Durbin, J L, Sullivan
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Primary Epstein-Barr virus infection

Journal of Clinical Virology, 2018
Epstein-Barr virus (EBV) infects about 90% of adults worldwide. It is the main cause of infectious mononucleosis, which is observed most frequently in adolescents. The disease can last several weeks and is characterized by lymphocytosis, sore throat, lymphadenopathy, and fatigue.
Samantha K, Dunmire   +2 more
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Epstein–Barr Virus Infection

New England Journal of Medicine, 2000
The Epstein–Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr.1 Four years later, in 1968, EBV was shown to be the etiologic agent of heterophile-positive infectious mononucleosis.2 EBV DNA was detected in tissues from patients with nasopharyngeal carcinoma ...
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Epstein‐Barr Virus Infection and Neoplasia

Otolaryngology–Head and Neck Surgery, 1981
Once acquired, Epstein‐Barr virus (EBV), a latent virus, remains in the body for what appears to be the lifetime of the human host. Circumstantial data suggest EBV is involved in clinical disease including malignancies far more often than previously recognized.
P M, Sprinkle, R W, Veltri
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Acyclovir and Epstein--Barr virus infection

Journal of Antimicrobial Chemotherapy, 1983
Acyclovir (ACV) has an ED50 of 0.3 microM against EBV replication in vitro. Based on these and other data we carried out a pilot, double-blind, placebo-controlled trial of ACV for treatment of infectious mononucleosis. Only patients with relatively severe illness requiring hospital management were enrolled.
J S, Pagano, J W, Sixbey, J C, Lin
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