Results 211 to 220 of about 6,458 (228)
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Impact of computerized dosing on eptifibatide-associated bleeding and mortality
American Heart Journal, 2009The study aimed to determine the impact on eptifibatide-associated bleeding by implementing a computerized dosing algorithm in the cardiac catheterization suite.Excessive dosing of eptifibatide is associated with increased bleeding rates and hospital mortality. Although dosing adjustments based on renal function has been recommended, its implementation
John M. Buergler +3 more
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Characterization of eptifibatide during drug formulation stability assays
Journal of Pharmaceutical and Biomedical Analysis, 2003The objective of the study was to determine the identity of a new impurity detected in HPLC chromatograms of research samples of eptifibatide manufactured by a new process and formulated into drug product. The identification of the unknown impurity was required in order to understand the mechanism of its formation.
Ronghua Wang +2 more
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Eptifibatide-Induced Thrombocytopenia—When Inhibitor Turns Killer
American Journal of Therapeutics, 2016Eptifibatide is a commonly and widely used drug for management of acute coronary syndrome and during percutaneous coronary intervention. It is usually well tolerated with no major adverse effects. We report a rare case of life-threatening thrombocytopenia secondary to eptifibatide along with a literature review of available evidence.
Abhishek Deshmukh +4 more
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The role of eptifibatide in patients undergoing percutaneous coronary intervention
Expert Opinion on Pharmacotherapy, 2007Glycoprotein (GP) IIb/IIIa receptor antagonists inhibit the binding of ligands to activated platelet GP IIb/IIIa receptors and, therefore, prevent the formation of platelet thrombi. They have been extensively studied in patients undergoing percutaneous coronary intervention (PCI).
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Association of eptifibatide and acute profound thrombocytopenia
The American Journal of Cardiology, 2001Bruce N. Brent, Richard Hongo
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Eptifibatide in Acute Coronary Syndromes
New England Journal of Medicine, 1999openaire +3 more sources