Results 81 to 90 of about 1,524,763 (305)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Menstruation and the Myth of the Gender-Neutral Worker: Structural Inequality in Labor Law

Laws
The legislative framework of labor law is generally described as gender-neutral based on universal presumptions about employment availability, work productivity, and the ability to work without interruption; in actuality, this gender-neutral framework ...
Bernadett Solymosi-Szekeres
doaj   +1 more source

Equal opportunities and treatment in employment and occupation [PDF]

Zbornik Radova Pravnog Fakulteta u Nišu, 2020
This paper analyzes international standards relating to discrimination in terms of employment and occupation, which are primarily contained in the legal instruments of the International Labor Organization.
Brković Radoje, Vučinić Dejan
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The updated ICRC Commentary on Geneva Convention IV: Bringing civilian protection into the twenty-first century

International Review of the Red Cross
Since their publication in the 1950s and 1980s respectively, the Commentaries on the Geneva Conventions of 1949 and their Additional Protocols of 1977 have become a major reference for the application and interpretation of those treaties.
Abhimanyu George Jain, Jean-Marie Henckaerts, Heleen Hiemstra, Kubo Mačák, Mikhail Orkin, Ellen Policinski, Matt Pollard   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Equal treatment of unsatisfied agents

Mathematical Social Sciences
In many models of resource allocation, agents are characterized by certain rights,needs, or demands. We impose the requirement that all agents who are not fullycompensated are assigned the same amount, and explore it in the models of claimsproblems, division problems with single-peaked preferences, and division problems with single-dipped preferences ...
Doudou Gong, Bas Dietzenbacher
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Equal-Treatment Policy in a Random Search Model with Taste Discrimination [PDF]

We consider a search model of the labor market with two types of equally productive workers and two types of firms, discriminators and non-discriminators. Without policy intervention, there is wage dispersion between and within the two worker groups, but
Lu, Jun, Kaas, Leo
core  

Insiders, Outsiders, and the Constructed Limits to Social Rights in EU Law

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(1), 163-190 | Article | (Table of Contents) 1. Introduction. – 2. The limitations of social rights of EU migrants. – 2.1. Secondary law. – 2.2.
Alezini Loxa
doaj   +1 more source