Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Changes in life expectancy and life span equality during the COVID-19 epidemic in 2020-22 in Japan. [PDF]
Okada Y, Nishiura H.
europepmc +1 more source
Equal contribution means that the contribution is equal
openaire +3 more sources
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Gender equality predicts female overrepresentation only in competitive domains where they have a relative advantage over males. [PDF]
Vishkin A, Krasner R, Wely M.
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
The Little Baby Bundle: An evaluation of a pilot scheme in Ireland
Iredale Rachel +3 more
doaj +1 more source
Conceptualising equity in basic medical education accreditation standards: A qualitative study of expert perspectives. [PDF]
Shaheen N, Mahboob U, Sethi A, Irfan M.
europepmc +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Advancing Climate Mitigation, Adaptation, and Equity Simultaneously: The Transformative Potential of Investments in Gender Equality. [PDF]
Heymann J +3 more
europepmc +1 more source

