Results 31 to 40 of about 2,102,601 (239)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Gender equality forum and spectrum respond to recent events around LSE men’s rugby [PDF]
, 2014 The Gender Equality Forum (GEF) and Spectrum (LSE’s LGBT+ staff forum) have released a joint statement in response to the sexist, homophobic, racist, and classist leaflet recently dispersed by the now disbanded LSE Men’s Rugby Club to LSE Freshers.
The Gender Equality Forum,
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
How Demanding Should Equality of Opportunity Be, and How Much Have We Achieved? [PDF]
, 2005 [Excerpt] This chapter proposes tests of various notions of equality of opportunity and applies them to intergenerational income data for the United States and Britain.
Gary S. Fields +4 more
core +2 more sources
Second order arithmetic means in operator ideals [PDF]
, 2007 Equality of the second order arithmetic means of two principal ideals does not imply equality of their first order arithmetic means (second order equality cancellation).
Kaftal, Victor, Weiss, Gary
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The equality of mixed partial derivatives under weak differentiability conditions
, 2014 We review and develop two little known results on the equality of mixed partial derivatives which can be considered the best results so far available in their respective domains.
Minguzzi, E.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Remainder Terms for Some Quantum Entropy Inequalities
, 2014 We consider three von Neumann entropy inequalities: subadditivity; Pinsker's inequality for relative entropy; and the monotonicity of relative entropy.
Carlen, Eric A., Lieb, Elliott H.
core +1 more source