Results 41 to 50 of about 37,156 (261)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Equality of Opportunity and Non-Discrimination
Sfera Politicii, 2012 This paper aims to explore the normative grounds of both equality of opportunity and non-discrimination, working with the underlying assumption of a connection between the two.
Ileana Dascălu
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Affirmative Action and Equality of Opportunity in College Admissions [PDF]
SHS Web of ConferencesThis essay critically examines the efficacy of race-based affirmative action in U.S. college admissions, arguing that it fails to adequately address the root causes of racial inequality and often does not benefit the most marginalized individuals within ...
Hamilton Ross, Deng Yinzhi
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The System Isn’t Broken. It’s Fixed
Religions, 2017 This paper has two distinct and related aims. First, I attempt to clarify the oft-made claim that somehow the “system is fixed”. What is meant by that charge and how is it distinct from other kinds of complaints with regard to economic inequality? Second,
Micah Lott
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Disclosure in Public Procurement in EU and German law الإفصاح في المشتريات العامة في قانون الإتحاد الأوربي والقانون الألماني [PDF]
مجلة حقوق دمياط للدراسات القانونية والاقتصاديةThis study compares the disclosure rules between the EU procurement law 2014 and Germany's Federal Public Procurement Act 2016. In the public procurement domain, transparency requirements stipulated under the EU directives can have different meanings in ...
Mohamed Abubakr Abdelmaqsoud Abdelhadi
doaj +1 more source