Studying longitudinal neutralising antibody levels against Equid herpesvirus 1 in experimentally infected horses using a novel pseudotype based assay [PDF]
Virus Research, 2023 Infection with equid herpesvirus 1 (EHV-1), a DNA virus of the Herpesviridae family represents a significant welfare issue in horses and a great impact on the equine industry.
Cecilia Di Genova +5 more
doaj +4 more sources
Environmental persistence of equid herpesvirus type‐1 [PDF]
Equine Veterinary Journal, 2020 Abstract Background Equid herpesvirus type 1 (EHV‐1) is ubiquitous in equine populations causing respiratory disease, and complications including late‐term abortion and neurological disease. Eradication of EHV‐1 from housing environments that typically contain unsealed wood and porous bedding ...
Nadia T. Saklou +4 more
openaire +5 more sources
A multiplex real-time PCR assay for detection of equid herpesvirus 1 and 4 [PDF]
Scientific ReportsEquid herpesvirus (EHV) 1 and -4 are common viral pathogens of horses that can cause upper respiratory disease, neurological disease, abortion, and death.
Rebecca L. Tallmadge +4 more
doaj +2 more sources
Epidemiological Aspects of Equid Herpesvirus-Associated Myeloencephalopathy (EHM) Outbreaks
Viruses, 2022 Equid Herpesvirus Myeloencephalopathy (EHM) is a multifactorial disease following an EHV-1 infection in Equidae. We investigated a total of 589 horses on 13 premises in Europe in search of risk factors for the development of EHM. We found that fever (p <
Eva Klouth +6 more
doaj +3 more sources
Viral Load and Cell Tropism During Early Latent Equid Herpesvirus 1 Infection Differ Over Time in Lymphoid and Neural Tissue Samples From Experimentally Infected Horses [PDF]
Frontiers in Veterinary Science, 2020 Upper respiratory tract infections with Equid Herpesvirus 1 (EHV-1) typically result in a peripheral blood mononuclear cell-associated viremia, which can lead to vasculopathy in the central nervous system.
Kim S. Giessler +11 more
doaj +2 more sources
Entry of equid herpesvirus 1 into CD172a+ monocytic cells
Journal of General Virology, 2016 Equid herpesvirus 1 (EHV-1) causes respiratory disease, abortion and neurological disorders in horses. Cells from the myeloid lineage (CD172a+) are one of the main target cells of EHV-1 during primary infection. Recently, we showed that EHV-1 restricts and delays its replication in CD172a+ cells as part of an immune-evasive strategy to disseminate to ...
Kathlyn, Laval +6 more
openaire +3 more sources
Identification of a Novel α-herpesvirus Associated with Ulcerative Stomatitis in Donkeys
Emerging Infectious Diseases, 2020 An outbreak of ulcerative stomatitis was observed in a donkey (Equus asinus) dairy herd. Similar lesions were also observed on the dams’ udders and, sporadically, in genital areas. The lesions typically resolved in 1–3 weeks.
Vito Martella +8 more
doaj +2 more sources
Modulation of Equid Herpesvirus-1 Replication Dynamics In Vitro Using CRISPR/Cas9-Assisted Genome Editing [PDF]
Viruses(1) Background: equid alphaherpesvirus-1 (EHV-1) is a highly contagious viral pathogen prevalent in most horse populations worldwide. Genome-editing technologies such as CRISPR/Cas9 have become powerful tools for precise RNA-guided genome modifications; (
Rabab T. Hassanien +4 more
doaj +2 more sources
Unmasking the ongoing challenge of equid herpesvirus- 1 (EHV-1): A comprehensive review [PDF]
Microbial PathogenesisEquid herpesviruses (EHVs) are a group of highly impactful viral pathogens that affect horses, presenting a substantial risk to the global equine industry. Among these, equid herpesvirus-1 (EHV-1) primarily causes respiratory infections. However, its ability to spread to distant organs can lead to severe consequences such as abortion and neurological ...
Ahmed F. Afify +4 more
openaire +4 more sources
Equid herpesvirus 8: Complete genome sequence and association with abortion in mares. [PDF]
PLoS ONE, 2018 Equid herpesvirus 8 (EHV-8), formerly known as asinine herpesvirus 3, is an alphaherpesvirus that is closely related to equid herpesviruses 1 and 9 (EHV-1 and EHV-9).
Marie Garvey +7 more
doaj +2 more sources