Results 51 to 60 of about 4,564 (251)

First glanders cases detected in Nepal underscore the need for surveillance and border controls

BMC Veterinary Research, 2022
Background Glanders is a transmissible zoonotic disease caused by Burkholderia mallei that infects equids and humans. No glanders cases in equids were reported so far in Nepal. Case presentation Following suspected glanders in animals with clinical signs
Koirala P, Maharjan M, Manandhar S, Pandey KR, Deshayes T, Wang G, Valvano MA, Laroucau K   +7 more
doaj   +1 more source

Complications associated with closed castration using the Henderson equine castration instrument in 300 standing equids.

, 2019
OBJECTIVE To describe a closed castration technique in standing equids, report associated complications, and identify potential risk factors. STUDY DESIGN Prospective cohort study of 300 standing equids that were castrated with the Henderson ...
Vidondo, Beatriz, Racine, Julien, Koch, Christoph, Ramseyer, Alessandra   +3 more
core   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Frequency and factors associated of potential zoonotic pathogens (Borrelia spp., Rickettsia spp., Leishmania spp., and Anaplasma phagocytophilum) in equids in the state of Bahia, Brazil

Parasites & Vectors, 2021
Background Currently, various zoonotic diseases are classified as emerging or reemerging. Because equids have a direct relationship with various vectors, they are possibly more frequently exposed to zoonotic agents than are humans.
Sonia Carmen Lopo Costa, Jéssica de Souza Freitas, Fábio Santos Carvalho, Maria Julia Salim Pereira, Matheus Dias Cordeiro, Adivaldo Henrique da Fonseca, Márcia Mariza Gomes Jusi, Rosangela Zacarias Machado, Alexandre Dias Munhoz   +8 more
doaj   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Meloxicam ameliorates the systemic inflammatory response syndrome associated with experimentally induced endotoxemia in adult donkeys

Journal of Veterinary Internal Medicine, 2020
Background Little information is available about endotoxemia in donkeys. Characterizing the systemic inflammatory response (SIRS) to lipopolysaccharide (LPS) in donkeys would provide valuable clinical and therapeutic information. The effects of meloxicam
Francisco Javier Mendoza Garcia, Carlos Gonzalez‐De Cara, Raul Aguilera‐Aguilera, Antonio Buzon‐Cuevas, Alejandro Perez‐Ecija   +4 more
doaj   +1 more source

Mitochondrial Phylogenomics of Modern and Ancient Equids [PDF]

PLoS ONE, 2013
The genus Equus is richly represented in the fossil record, yet our understanding of taxonomic relationships within this genus remains limited. To estimate the phylogenetic relationships among modern horses, zebras, asses and donkeys, we generated the first data set including complete mitochondrial sequences from all seven extant lineages within the ...
Weinstock, J., Vilstrup, J.T., Seguin-Orlando, A., Stiller, M., Ginolhac, A., Raghavan, M., Nielsen, S.C.A., Froese, D., Vasiliev, S.K., Ovodov, N.D., Clary, J., Helgen, K.M., Fleischer, R.C., Copper, A., Shapiro, B., Orlando, L.   +15 more
openaire   +7 more sources

Use of a painless external fixator for unilateral mandibular fracture repair in nine equids

, 2010
OBJECTIVE: To report use of a pinless external fixator (PEF) for unilateral mandibular fractures in 9 equids. STUDY DESIGN: Case series. ANIMALS: Equids (n=9) with unilateral mandibular fractures.
Caroline Tessier, Tessier, C., Rhea Maria Anna Haralambus, Haralambus, R.M., Brehm, W., Werren, C., Walter Brehm, Cecile Werren   +7 more
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Long‐Term Response of Equids With Pituitary Pars Intermedia Dysfunction to Treatment With Pergolide

Journal of Veterinary Internal Medicine
Background Limited data document long‐term responses of equids with pituitary pars intermedia dysfunction (PPID) to pergolide treatment. Objectives Report clinical response, medical problems, outcome, and owner satisfaction with pergolide treatment of ...
Harold C. Schott II, Julie R. Strachota, Judith V. Marteniuk, Kent R. Refsal   +3 more
doaj   +1 more source