Results 41 to 50 of about 10,475,713 (159)

Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract The landscape of Alzheimer's disease (AD) and related dementias (ADRD) diagnosis is evolving rapidly, driven by advances in disease understanding, biomarker tools, and disease‐modifying therapies. Modern diagnostic approaches emphasize biological precision, early detection, and dynamic frameworks that adapt to treatment‐induced changes in ...
Takeshi Iwatsubo, Reisa A. Sperling, Alicia Algeciras‐Schimnich, Hidenori Arai, Anna M. Barron, Tammie L. S. Benzinger, Maria C. Carrillo, Christopher Chen, Seong Hye Choi, Igor C. Fontana, Jonathan Graff‐Radford, Joshua D. Grill, Judith Heidebrink, Chaur‐Jong Hu, Ryoko Ihara, Takeshi Ikeuchi, Atsushi Iwata, Fanny C. F. Ip, Fasihah Irfani Fitri, Clifford R. Jack Jr., Jee Hyang Jeong, Jianping Jia, Nagaendran Kandiah, SangYun Kim, Hisatomo Kowa, Renaud La Joie, Yoshiki Niimi, Ryoji Noritake, Ozioma C. Okonkwo, Sebastian Palmqvist, Michael S. Rafii, Rema Raman, Yong Shen, Tanya Simuni, Heather M. Snyder, Orapitchaya Sriwannopas, Luke E. Stoeckel, Wiesje M. van der Flier, Huali Wang, Donna M. Wilcock, Henrik Zetterberg, Jin Zhou, Simin Mahinrad, Claire E. Sexton   +43 more
wiley   +1 more source

Subcortical gray matter volumes and 5‐year dementia risk in individuals with subjective cognitive decline or mild cognitive impairment: A multi‐cohort analysis

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION The prognostic value of subcortical gray matter structures for dementia beyond the hippocampus remains unclear. METHODS We included participants with subjective cognitive decline or mild cognitive impairment from two memory clinic‐based cohorts (Amsterdam Dementia Cohort and National Alzheimer's Coordinating Center) and one ...
Mathijs T. Rosbergen, Pieter van der Veere, Jacqueline J. Claus, Tavia E. Evans, Vikram Venkatraghavan, Frederik Barkhof, Argonde C. van Harten, M. Arfan Ikram, Wiesje M. van der Flier, Meike W. Vernooij, Frank J. Wolters   +10 more
wiley   +1 more source

La valoración económica de cambios en servicios del ecosistema: Una aplicación de la metodología CGE

Economía Agraria y Recursos Naturales, 2011
El presente estudio integra en la modelización de Equilibrio General Computable (EGC) los servicios de la biodiversidad, proponiendo una metodología para la evaluación de impactos del cambio climático en los ecosistemas.
Francesco Bosello, Fabio Eboli, Ramiro Parrado, Paolo A.L.D. Nunes, Helen Ding, Renato Rosa   +5 more
doaj   +1 more source

SCD‐plus features and AD biomarkers in cognitively unimpaired samples: A meta‐analytic approach for nine cohort studies

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Specific features of subjective cognitive decline (SCD‐plus) have been proposed to indicate an increased risk of preclinical Alzheimer's disease (AD). However, few studies have examined how these features relate to AD biomarkers in cognitively unimpaired (CU) older adults. METHODS Meta‐analyses were performed using cross‐sectional
Elizabeth Kuhn, Hannah M. Klinger, Rebecca E. Amariglio, Michael Wagner, Frank Jessen, Emrah Düzel, Michael T. Heneka, Gael Chételat, Dorene M. Rentz, Reisa A. Sperling, Jarith L. Ebenau, Elke Butterbrod, Wiesje M. Van Der Flier, Sietske A. M. Sikkes, Charlotte E. Teunnissen, Argonde C. Van Harten, Elsmarieke M. Van De Giessen, Lorena Rami, Adria Tort, Gonzalo Sánchez Benavides, Katherine A. Gifford, Carol Van Hulle, Rachel F. Buckley, Alzheimer's Disease Neuroimaging Initiative, Australian Imaging Biomarkers and Lifestyle flagship study of ageing, A4 Study Team, DELCODE Study, Harvard Aging Brain Study, Frederic Brosseron, Katharina Buerger, Christoph Laske, Robert Perneczky, Oliver Peters, Joseph Priller, Alfredo Ramirez, Anja Schneider, Annika Spottke, Stefan Teipel, Jens Wiltfang   +38 more
wiley   +1 more source

The platform policy matrix: Promotion and regulation

Policy &Internet, Volume 17, Issue 1, March 2025.
Abstract This study provides a comprehensive analysis of policy measures adopted by countries in response to the rapid growth of digital platforms, which significantly impact various sectors and national economies. It examines the delicate balance between regulation and innovation, offering nuanced policy recommendations.
Junic Kim, Shanghe Ahn
wiley   +1 more source

Calibración de un modelo de equilibrio general computable para la economía chilena y estructura de simulaciones [PDF]

Estudios de Economia, 1988
El trabajo tiene por objeto presentar la calibración de un modelo computable de equilibrio general para la economía chilena. El modelo representa la estructura de una pequeña y abierta economía, de cuatro sectores, con precios relativos de bienes endógenos y precios relativos de factores exógenos.
Ivulic, Yerka, Schmidt-Hebbel, Klaus
openaire  

Defining benefit: Clinically and biologically meaningful outcomes in the next‐generation Alzheimer's disease clinical care pathway

Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Abstract To understand the potential benefits of emerging Alzheimer's disease (AD) therapies within and beyond clinical trial settings, there is a need to advance current outcome measurements into meaningful information relevant to all stakeholders. The relationship between the impact on disease biology and clinically measurable outcomes in cognition ...
Aya Elhage, Sharon Cohen, Jeffrey Cummings, Wiesje M. van der Flier, Paul Aisen, Min Cho, Joanne Bell, Harald Hampel   +7 more
wiley   +1 more source

General Equilibrium Models: An Overview [PDF]

This article reviews the literature on general equilibrium models, relevant to the Chilean economy, and revised versions of the papers presented at the Conference of General Equilibrium Models for the Chilean Economy organized by the Central Bank of ...
Klaus Schmidt-Hebbel, Rómulo A. Chumacero   +1 more
core   +2 more sources

Efeitos da ampliação das exportações agropecuárias e agroindustriais na balança comercial e (re)distribuição da renda: uma análise de equilíbrio geral

Revista de Economia e Sociologia Rural, 2006
O objetivo deste trabalho foi analisar os efeitos da ampliação das exportações agropecuárias e agroindustriais brasileiras sobre a balança comercial e (re)distribuição de renda entre fatores de produção, em um contexto de equilíbrio geral, tendo-se por ...
Neiva de Araújo Marques, Wilson da Cruz Vieira, Viviani Silva Lírio, Suely de Fátima Ramos Silveira   +3 more
doaj   +1 more source

Pooling Alzheimer's disease clinical trial data to develop personalized medicine approaches is easier said than done: A proof‐of‐principle study and call to action

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 10, Issue 3, July‐September 2024.
Abstract With the advent of the first generation of disease‐modifying treatments for Alzheimer's disease, it is clearer now more than ever that the field needs to move toward personalized medicine. Pooling data from past trials may help identify subgroups most likely to benefit from specific treatments and thus inform future trial design.
Mark A. Dubbelman, Eleonora M. Vromen, Betty M. Tijms, Johannes Berkhof, Lois Ottenhoff, Everard G. B. Vijverberg, Niels D. Prins, Wiesje M. van der Flier, Sietske A. M. Sikkes   +8 more
wiley   +1 more source