Results 91 to 100 of about 3,435,186 (300)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Local stability analysis of equilibrium points (Proposition 5).

open access: yes, 2021
Local stability analysis of equilibrium points (Proposition 5).
Xinchun Li (551742)   +2 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Altruistic Behavior and Correlated Equilibrium Selection [PDF]

open access: yes
This paper studies new refinement concepts for correlated equilibria based on altruistic behavior of the players and which generalize some refinement concepts introduced by the authors in previous papers for Nash equilibria. Effectiveness of the concepts,
Jacqueline Morgan, Giuseppe De Marco
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Strategic Equilibrium [PDF]

open access: yes
An outcome in a noncooperative game is said to be self-enforcing, or a strategic equilibrium, if, whenever it is recommended to the players, no player has an incentive to deviate from it.This paper gives an overview of the concepts that have been ...
Damme, E.E.C. van
core  

The evolutionary phase diagrams of equilibrium points.

open access: yes
The evolutionary phase diagrams of equilibrium points.
Zhen Xu (92379), Shudan Zheng (4348339)
core   +1 more source

Two stage stochastic equilibrium problems with equilibrium constraints: modeling and numerical schemes

open access: yes, 2010
This paper presents a two stage stochastic equilibrium problem with equilibrium constraints (SEPEC) model. Some source problems which motivate the model are discussed. Monte Carlo sampling method is applied to solve the SEPEC. Convergence analysis on the
Xu, Huifu, Zhang, Dali
core   +1 more source

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