Results 91 to 100 of about 3,091,503 (255)
Altruistic Behavior and Correlated Equilibrium Selection [PDF]
This paper studies new refinement concepts for correlated equilibria based on altruistic behavior of the players and which generalize some refinement concepts introduced by the authors in previous papers for Nash equilibria. Effectiveness of the concepts,
Jacqueline Morgan, Giuseppe De Marco
core
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
The evolutionary phase diagrams of equilibrium points.
The evolutionary phase diagrams of equilibrium points.
Zhen Xu (92379), Shudan Zheng (4348339)
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2010 This paper presents a two stage stochastic equilibrium problem with equilibrium constraints (SEPEC) model. Some source problems which motivate the model are discussed. Monte Carlo sampling method is applied to solve the SEPEC. Convergence analysis on the
Xu, Huifu, Zhang, Dali
core +1 more source
Global games and equilibrium selection [PDF]
Game Theory;Equilibrium ...
Carlsson, H., Damme, E.E.C. van
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Equilibrium points and their stability of COVID-19 in US
Scientific ReportsThis study aims to develop an advanced mathematic model and investigate when and how will the COVID-19 in the US be evolved to endemic. We employed a nonlinear ordinary differential equations-based model to simulate COVID-19 transmission dynamics ...
Xiaoxi Hu +8 more
doaj +1 more source
Mathematical modeling applied to understand the host-pathogen interaction of HIV infection in Bangladesh [PDF]
Surveys in Mathematics and its Applications, 2017 The most urgent public health problem today is to devise effective strategies to minimize the destruction caused by the AIDS epidemic. The understanding of HIV infection through mathematical modeling have made a significant contribution.
S. K. Sahani +2 more
doaj