Results 41 to 50 of about 269,155 (257)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Dynamical environment in the vicinity of asteroids with an application to 41 Daphne
Results in Physics, 2018 We studied the dynamical environment in the vicinity of the primary of the binary asteroid. The gravitational field of the primary is calculated by the polyhedron model with observational data of the irregular shape. The equilibrium points, zero-velocity
Yu Jiang
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
MathematicsThis research employs the improved modified extended tanh-function technique to explore several solitary wave solutions to the fractional-order Fokas equation.
M. B. Almatrafi
doaj +1 more source
On the Properties of a Class of Impulsive Competition Beverton–Holt Equations
Applied Sciences, 2021 This paper is devoted to a type of combined impulsive discrete Beverton–Holt equations in ecology when eventual discontinuities at sampling time instants are considered.
Manuel De la Sen +4 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Fixed points, intersection theorems, variational inequalities, and equilibrium theorems
International Journal of Mathematics and Mathematical Sciences, 2000 From a fixed point theorem for compact acyclic maps defined on admissible convex sets in the sense of Klee, we first deduce collectively fixed point theorems, intersection theorems for sets with convex sections, and quasi-equilibrium theorems.
Sehie Park
doaj +1 more source
ON COMPUTATIONAL DIFFERENCES OF CRITICAL POINTS ON EQUILIBRIUM CURVE
International Journal for Computational Civil and Structural Engineering, 2017 In this paper, we discuss the features of investigating the type of the critical point on the equilibrium curve (bifurcation point or limit point). There are new ideas about the completion of the initial equilibrium at the limit point or bifurcation ...
Gaik A. Manuylov +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source