Results 61 to 70 of about 2,630,658 (252)

PROFILE Trial Protocol V6.0

open access: yes, 2023
PROFILE Trial Protocol V6.
PROFILE Trial
core   +1 more source

Theoretical study on the movements of bubbles

open access: yesUltrasonics Sonochemistry
The radial and translational motions of multiple interacting spherical bubbles are obtained using classical Newton mechanics. It is seen that bubbles not only move in straight line, but also in circular motion.
Lingling Zhang, Weizhong Chen
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

The uncertainty quantification of the free boundary G–S plasma equilibrium calculation on Experimental Advanced Superconducting Tokamak (EAST)

open access: yesNuclear Fusion
The precision of plasma equilibrium is a pivotal issue in the field of magnetic confinement fusion plasma physics and the operation of tokamak plasmas. During the plasma equilibrium uncertainty quantification (UQ) assessment process, input parameters for
S.Z. Yuan   +11 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Movable-Bed Modeling Law for Beach Response Experiments Using Equilibrium Beach Profile Formula

open access: yes한국해양공학회지, 2018
The construction of large scale harbor structures at Maengbang beach, which is located on the eastern coast of Korea, is of great concern because it may cause disastrous beach erosion in the vicinity. Therefore, a hydraulic model experiment was conducted
Jin Hoon Kim, In Ho Kim, Jung Lyul Lee
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Optimized point dose measurement: An effective tool for QA in intensity-modulated radiotherapy

open access: yesJournal of Medical Physics, 2007
In some cases of Intensity-modulated radiotherapy (IMRT) point dose measurement, there exists significant deviation between calculated and measured dose at isocenter, sometimes greater than ±3%.
Kumar Alok   +4 more
doaj  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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