Results 41 to 50 of about 380,487 (338)

A forage-only diet alters the metabolic response of horses in training [PDF]

, 2012
Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from
A. Jansson, Connysson, Connysson, Danielsen, Devlin, Ellis, Essén-Gustavsson, Essén-Gustavsson, Farris, Geor, Gillham, Glade, Harris, Hintz, Houpt, Hudson, Hyyppä, J.E. Lindberg, Kelso, Lacombe, Lacombe, Lawrence, Lindholm, Lowry, Luthersson, MacLeay, Meyer, Muhonen, Pagan, Palmgren-Karlsson, Palmgren-Karlsson, Persson, Potter, Ragnarsson, Redbo, Schuback, Snow, Tinker, Voiton, Waller, Waller, Waters, Willard, Williamson, Willing, Wilson   +45 more
core   +2 more sources

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Characterization and profiling of immunomodulatory genes of equine mesenchymal stromal cells from non-invasive sources [PDF]

, 2014
Introduction: Mesenchymal stromal cells (MSCs) have been extensively studied for their promising capabilities in regenerative medicine. Although bone marrow is the best-known source for isolating equine MSCs, non-invasive alternative sources such as ...
De Schauwer, Catharina, Goossens, Karen, Govaere, Jan, Hoogewijs, Maarten, Meyer, Evelyne, Piepers, Sofie, Smits, Katrien, Van de Walle, Gerlinde, Van Soom, Ann   +8 more
core   +2 more sources

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source

Use of nuclear medicine imaging: Scintigraphy in diagnosis of equine orthopedic disease [PDF]

Veterinarski Glasnik, 2002
This study describes techniques, indications and findings of nuclear medicine imaging – scintigraphy of 42 horses with acute and chronic lameness of unknown origin. Most horses showed increased uptake of 99mTc-methylene diphosphonate in the tarsal joint (
Kovač Milomir, Nowak Michael, Petzoldt S., Tambur Zoran   +3 more
doaj   +1 more source

Equine nutrition: a preliminary investigation of feeding practices in equine veterinary hospitals in the USA [PDF]

, 2018
Nutrition plays an important role in equine rehabilitation, with contradictory approaches existing on correct nutritional management of patients. The preponderance of information related to nutrient requirements for horses was designed for healthy ...
Garber, Anna, Hastie, Peter, Kaya Karasu, Gulsah, Murray, Jo-Anne, Park, Katarina, Robert, Jayne   +5 more
core  

Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries [PDF]

, 2016
Aim: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDC) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix. Methods: Explants from equine
Dudhia, J, Garvican, E R, Salavati, M, Smith, R K W   +3 more
core   +3 more sources

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Osteochondrosis lesions of the lateral trochlear ridge of the distal femur in four ponies [PDF]

, 2011
Lesions of the lateral trochlear ridge (LTR) of the distal femur were investigated in four pony or pony cross horses. The animals were all geldings and were six to 15 months of age.
Henson, F.M.D., Jeffcott, L.B., Platt, D., Voute, L.C.   +3 more
core   +1 more source

From Solution to Surface: How the Catalytic Environment Modulates Peptide Bond Cleavage by Metal‐Oxo Cluster Nanozymes

Advanced Science, EarlyView.
Comparison of homogeneous Hf12(sol) and heterogeneous Hf12(precip) metal‐oxo clusters enables investigation of how solubility influences nanozymatic reactivity and selectivity toward proteolysis, without introducing confounding factors from differences in cluster identity.
Kilian Declerck, Muhammed Jibin Parammal, Carlotta Seno, Thomas J. N. Hooper, Dimitrios Sakellariou, Jonathan De Roo, Nada D. Savić, Tatjana N. Parac‐Vogt   +7 more
wiley   +1 more source