Results 71 to 80 of about 195,534 (268)

Dexamethasone: a double-edged sword in the treatment of osteoarthritis

Scientific Reports
Glucocorticoids are widely used to manage osteoarthritis (OA) symptoms, but long-term safety concerns exist. This study investigates the therapeutic potential of dexamethasone (DEX) and triamcinolone acetonide (TA) in chondrocytes, evaluating their anti ...
Karyna Tarasova, Maria Belen Arteaga, Angkana Kidtiwong, Sinan Gueltekin, Andrea Bileck, Christopher Gerner, Iris Gerner, Florien Jenner   +7 more
doaj   +1 more source

Idiopathic peritonitis in horses: a retrospective study of 130 cases in Sweden (2002–2017)

Acta Veterinaria Scandinavica, 2019
Background Peritonitis in horses is historically associated with prolonged treatment regimens of broad-spectrum antimicrobials and a guarded prognosis for survival.
Emma Odelros, Anna Kendall, Ylva Hedberg-Alm, John Pringle   +3 more
doaj   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

Evaluation of peritoneal l‐lactate concentration in horses in the early post‐partum period

Veterinary Medicine and Science
Background Peritoneal fluid lactate concentration is an important diagnostic tool in horses with abdominal pain. Information on peritoneal lactate concentrations is lacking following parturition in the mare.
Giulia Rapezzano, Marco Marcatili, Richard Stephenson, Regina Pereira, Gayle Hallowell, Marco Duz   +5 more
doaj   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Impact of evidence‐based information on horse owners' misconceptions of colic

Equine Veterinary Journal, EarlyView.
Abstract Background Misconceptions can be defined as ‘false, persistent beliefs’ or ‘inaccurate, prior knowledge’ and can influence decision‐making. Objectives To investigate the impact of evidence‐based information on UK horse owners' decision‐making for colic. Study Design Mixed‐methods cross‐sectional study.
K. L. Burrell, G. C. W. England, J. H. Burford, S. L. Freeman   +3 more
wiley   +1 more source

Validation of a stall‐side immunoglobulin assay for use in equine reproductive management

Equine Veterinary Journal, EarlyView.
Abstract Background Equine foals receive IgG from mare colostrum through passive transfer. Failure of passive transfer (FPT) is a significant risk to the foal's life, leaving them vulnerable to infection and sepsis. Radial Immunodiffusion (RID) and immunoturbidimetric assays quantify IgG present in a foal sample but require a laboratory to complete ...
L. Moore, A. McLain, S. H. McDowell, C. J. Ledgerwood, E. Bailie, M. A. Nesbit, T. Moore   +6 more
wiley   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source

Subclinical infection and potential shedding routes of equine parvovirus‐hepatitis among hospitalized horses in Austria

Journal of Veterinary Internal Medicine
Background Equine parvovirus hepatitis (EqPV‐H) can cause Theiler's disease and subclinical hepatitis in horses. Objectives Assess the frequency of subclinical EqPV‐H infection in hospitalized horses and to study viral transmission by investigating ...
Dilara Lale, Esther E. Dirks, Irina Preining, Manolis Lyrakis, Andre Gömer, Eike Steinmann, Jessika‐M. V. Cavalleri, Anna Sophie Ramsauer   +7 more
doaj   +1 more source

The Role of Equestrian Professionals in Saddle Fit for Horses and Riders in the United Kingdom

Animals
The horse owner and the multi-disciplinary team (MDT) are responsible for safeguarding horse welfare by ensuring the equipment being used is correctly fitted. The aim of this study was to investigate how saddle fit is assessed, managed, and acted upon by
Russell MacKechnie-Guire, Jane M. Williams, Diana Fisher, Kathryn Nankervis   +3 more
doaj   +1 more source