Results 71 to 80 of about 415,267 (362)

Spread of the emerging equine-like G3P[8] DS-1-like genetic backbone rotavirus strain in Brazil and identification of potential genetic variants.

Journal of General Virology, 2019
In 2013, the equine-like G3P[8] DS-1-like rotavirus (RVA) strain emerged worldwide. In 2016, this strain was reported in northern Brazil. The aims of the study were to conduct a retrospective genetic investigation to identify the possible entry of these ...
Adriana Luchs, A. C. da Costa, A. Cilli, S. Komninakis, R. Carmona, L. Boen, S. G. Morillo, E. Sabino, M. C. Timenetsky   +8 more
semanticscholar   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Improving the Recognition of Equine Affective States

Animals, 2019
Simple Summary People commonly fail to recognise the behavioural signs that horses display when they experience pain and fear. Consequently, the distress remains unresolved, reducing the horse’s welfare and having potential safety implications for the ...
Catherine Bell, S. Rogers, Julie Taylor, D. Busby   +3 more
semanticscholar   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source

A forage-only diet alters the metabolic response of horses in training [PDF]

, 2012
Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from
A. Jansson, Connysson, Connysson, Danielsen, Devlin, Ellis, Essén-Gustavsson, Essén-Gustavsson, Farris, Geor, Gillham, Glade, Harris, Hintz, Houpt, Hudson, Hyyppä, J.E. Lindberg, Kelso, Lacombe, Lacombe, Lawrence, Lindholm, Lowry, Luthersson, MacLeay, Meyer, Muhonen, Pagan, Palmgren-Karlsson, Palmgren-Karlsson, Persson, Potter, Ragnarsson, Redbo, Schuback, Snow, Tinker, Voiton, Waller, Waller, Waters, Willard, Williamson, Willing, Wilson   +45 more
core   +2 more sources

Antimicrobial peptides secreted by equine mesenchymal stromal cells inhibit the growth of bacteria commonly found in skin wounds

Stem cell research & therapeutics, 2017
BackgroundThe prevalence of chronic skin wounds in humans is high, and treatment is often complicated by the presence of pathogenic bacteria. Therefore, safe and innovative treatments to reduce the bacterial load in cutaneous wounds are needed ...
R. Harman, Steven H. Yang, Megan K. He, G. R. Van de Walle   +3 more
semanticscholar   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Osteochondrosis lesions of the lateral trochlear ridge of the distal femur in four ponies [PDF]

, 2011
Lesions of the lateral trochlear ridge (LTR) of the distal femur were investigated in four pony or pony cross horses. The animals were all geldings and were six to 15 months of age.
Henson, F.M.D., Jeffcott, L.B., Platt, D., Voute, L.C.   +3 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Equine coronavirus infection and replication in equine intestinal enteroids

Veterinary Research
In this study, equine intestinal enteroids (EIEs) were generated from the duodenum, jejunum, and ileum and inoculated with equine coronavirus (ECoV) to investigate their suitability as in vitro models with which to study ECoV infection ...
Yoshinori Kambayashi, Manabu Nemoto, Akihiro Ochi, Daiki Kishi, Takanori Ueno, Koji Tsujimura, Hiroshi Bannai, Nanako Kawanishi, Minoru Ohta, Tohru Suzuki   +9 more
doaj   +1 more source