Results 51 to 60 of about 18,800 (310)
Advanced Science, EarlyView.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source
TGF-β inhibitor SB431542 suppresses SARS-CoV-2 replication through multistep inhibition
Journal of VirologyThe coronavirus disease 2019 (COVID-19) pandemic highlighted the critical need for broad-spectrum antivirals with high resistance barriers. Here, we demonstrate that SB431542, a selective TGF-β receptor I (ALK5) inhibitor, exhibits potent antiviral ...
Assim Verma +17 more
doaj +1 more source
Australian Journal of Social Issues, EarlyView.ABSTRACT While Australia's National Disability Insurance Scheme (NDIS) was founded on principles of choice and control, for people with significant mental health challenges (what the NDIS calls ‘psychosocial disability’) these ideals often remain elusive. Support systems continue to be fractured and in the context of ongoing policy reforms, it is vital
Joel Hollier, Jennifer Smith‐Merry
wiley +1 more source
Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
The MicrobeRhodococcus equi is a gram-positive, facultative intracellular bacterial pathogen which causes persistent purulent bronchopneumonia in foals less than six months of age.
Punit Jhandai +3 more
doaj +1 more source
Detection of natural prevalence and infection of ixodid ticks with Theileria equi in hilly equines of Palam valley (India) [PDF]
Veterinary World, 2014 Aim: The aim was to study the prevalence of tick infestation in equines of Palam valley and specific detection of Theileria equi infection in tick samples with nested polymerase chain reaction (PCR) based assay.
Prateek Kashyap +2 more
doaj +1 more source
Serosurveillance of infectious agents in equines of the Central Valley of Costa Rica [PDF]
, 2014 Blood samples from 181 equines from the Central Valley of Costa Rica were collected in the year 2012 to determine the presence of antibodies against selected infectious agents in horses and to determine the risk factors associated with these agents.
D. Jiménez +2 more
core +2 more sources
The Anatomical Record, EarlyView.Domestic rabbits of different body sizes differ disproportionately in the length of their tooth row or the length of their diastema. Abstract In various domestic mammals, smaller breeds tend to have proportionally larger teeth, whereas this is not a universal trend across mammals.
Ursina L. Fasciati +3 more
wiley +1 more source
A two-year participatory intervention project with owners to reduce lameness and limb abnormalities in working horses in Jaipur, India [PDF]
, 2015 Participatory methods are increasingly used in international human development, but scientific evaluation of their efficacy versus a control group is rare. Working horses support families in impoverished communities.
A Tsutsumi +30 more
core +3 more sources
The Anatomical Record, EarlyView.Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira +3 more
wiley +1 more source