Results 41 to 50 of about 1,115,400 (219)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

УСЕРЕДНЕНІ ПОКАЗНИКИ ВАРТОСТІ ЕКСПЛУАТАЦІЇ ДОРОЖНІХ МАШИН ТА МЕХАНІЗМІВ. ПРОБЛЕМИ ТЕХНІЧНОГО ОСНАЩЕННЯ ДЕРЖАВНИХ ДОРОЖНІХ ПІДПРИЄМСТВ

open access: yesInternational Journal of Innovative Technologies in Economy, 2021
Важко переоцінити значення дорожньо-будівельної галузі для економічного розвитку будь-якої країни. Зокрема, за даними Київської школи економіки (KSE), довгострокові ефекти в результаті реалізації інфрастуктурної програми «Велике будівництво», велика ...
Yuliya Bibyk   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

MODELING OF PROCESSES OF REPAIR OF ENERGY EQUIPMENT

open access: yesВестник университета, 2019
In the article the correlation analysis by means of which the author establishes qualitative extent of influence of eleven factors on value of net profit of the enterprise of a power complex is submitted.
A. Ievlev
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

INNOVATION MANAGEMENT OF MAINTENANCE OF MILITARY TECHNIQUE OF THE VIETNAMESE PEOPLE'S ARMY BASED ON NETWORK PLANNING

open access: yesВестник университета, 2019
In the article the application of network planning in organizing the maintenance of military equipment of the Vietnamese People's Army is presented. The orderliness and principle for building network charts have been formed.
M. C. Nguyen, I. Ivanov
doaj  

PROJECT MANAGEMENT OF CROPS GROWING TECHNOLOGICAL SYSTEMS

open access: yesВісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2016
The technological system of crops growing is determined. The project environment is uncategorized. The features of project management of technological systems are determined.
Павло Миронович ЛУБ   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Research Progress on Mechanization Technology and Equipment for Cassava Field Production

open access: yesAgriculture
Cassava is one of the world’s staple crops and an important economic and food crop for one billion people. It holds significant value in food, feed, and industrial raw materials.
Guojie Li   +12 more
doaj   +1 more source

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