Results 41 to 50 of about 316,168 (290)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Comparative Study of Patient Satisfaction, Physical Space and Medical Equipment between Governmental and Private Hospitals

نشریه پرستاری ایران, 2009
Background and Aim: Quality of services in hospitals should be continuously evaluated in terms of structure, process, and outcome. The purpose of this study was to comparepatient satisfaction, physical space and medical equipment between governmental and
Masoumeh Seidi, Akram Heidary, Ashraf Khorramy-Rad, Hoda Ahmary-Tehran   +3 more
doaj  

Beyond good intentions: lessons on equipment donation from an African hospital

Bulletin of the World Health Organization
OBJECTIVE: In 2000, a referral hospital in the Gambia accepted a donation of oxygen concentrators to help maintain oxygen supplies. The concentrators broke down and were put into storage.
Stephen RC Howie, Sarah E Hill, David Peel, Momodou Sanneh, Malick Njie, Philip C Hill, Kim Mulholland, Richard A Adegbola   +7 more
doaj   +1 more source

IoT enabled hospital asset tracking using advanced interdisciplinary approaches [PDF]

E3S Web of Conferences
As the healthcare landscape embraces the revolutionary power of digitalization, improving inventory systems has become a top priority. Hospital asset tracking primarily focuses on monitoring various assets within a healthcare facility.
Saritha K., Abhiram Cherukuri, Anvith Reddy Poreddy, Sai Sathwik Sundralla, Rasool Shaik Nayab, Alzubaidi Laith H., Helena Raj Vijilius, Dutt Amit, Kumar Yadav Dinesh   +8 more
doaj   +1 more source

Preparing for a COVID-19 pandemic: Redefining roles of multidisciplinary team in a large tertiary hospital in Rajasthan

Journal of Family Medicine and Primary Care, 2020
Through this manuscript, we would like to share our experience with building a COVID hospital, allocating duties, planning and managing supplies during COVID-19 pandemic.
Abhay Elhence, Binit Sureka, Mahendra Kumar Garg, Pankaj Bhardwaj, Tanuj Kanchan, Arvind Sinha, Pradeep Kumar Bhatia, Vijaya Lakshmi Nag, Nikhil Kothari, Naveen Dutt, Suryanarayanan Bhaskar, Vibhor Tak, N R Bishnoi, Sanjeev Misra   +13 more
doaj   +1 more source

Developing a patient measure of safety (PMOS) [PDF]

, 2013
Background: Tools that proactively identify factors that contribute to accidents have been developed within high-risk industries. Although patients provide feedback on their experience of care in hospitals, there is no existing measure which asks ...
Ashley, Baillie, Blenkinsopp, Bloor, Castle, DeVellis, Dougall, Egberts, Fitzpatrick, Giles, Goldstein, Hinchcliff, Hinkin, Hollway, Jenkinson, Lawton, Neuendorf, Pettersen, Schwappach, Sitzia, Stone, van Someren, Ward, Ward, Watt, Weingart, Weingart, Weissman, Williams   +28 more
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Availability of facilities and equipment to provide emergency care in ambulances, which transport patients to the National Hospital of Sri Lanka

Journal of the College of Community Physicians, 2019
Objective To describe available facilities and equipment in ambulances, to provide essential emergency care, which transport patients to the National Hospital of Sri Lanka Methods A descriptive cross-sectional hospital based study was carried out at the
Gangadevi Nandasena, Chrisantha Abeysena
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source