Results 41 to 50 of about 48,752 (298)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Essential Emergency Surgical Care in remote hilly districts of Karnali Province - A Cross-Sectional Survey

Journal of Karnali Academy of Health Sciences, 2020
Background: Remote hilly areas of Karnali province has one in all the very best burdens of surgically treatable conditions within the world and therefore, the highest unmet need.
Praveen Kumar Giri, Prem Prasad Panta, Niresh Thapa   +2 more
doaj   +2 more sources

Comparative Study of Patient Satisfaction, Physical Space and Medical Equipment between Governmental and Private Hospitals

نشریه پرستاری ایران, 2009
Background and Aim: Quality of services in hospitals should be continuously evaluated in terms of structure, process, and outcome. The purpose of this study was to comparepatient satisfaction, physical space and medical equipment between governmental and
Masoumeh Seidi, Akram Heidary, Ashraf Khorramy-Rad, Hoda Ahmary-Tehran   +3 more
doaj  

Preparing for a COVID-19 pandemic: Redefining roles of multidisciplinary team in a large tertiary hospital in Rajasthan

Journal of Family Medicine and Primary Care, 2020
Through this manuscript, we would like to share our experience with building a COVID hospital, allocating duties, planning and managing supplies during COVID-19 pandemic.
Abhay Elhence, Binit Sureka, Mahendra Kumar Garg, Pankaj Bhardwaj, Tanuj Kanchan, Arvind Sinha, Pradeep Kumar Bhatia, Vijaya Lakshmi Nag, Nikhil Kothari, Naveen Dutt, Suryanarayanan Bhaskar, Vibhor Tak, N R Bishnoi, Sanjeev Misra   +13 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

IoT enabled hospital asset tracking using advanced interdisciplinary approaches [PDF]

E3S Web of Conferences
As the healthcare landscape embraces the revolutionary power of digitalization, improving inventory systems has become a top priority. Hospital asset tracking primarily focuses on monitoring various assets within a healthcare facility.
Saritha K., Abhiram Cherukuri, Anvith Reddy Poreddy, Sai Sathwik Sundralla, Rasool Shaik Nayab, Alzubaidi Laith H., Helena Raj Vijilius, Dutt Amit, Kumar Yadav Dinesh   +8 more
doaj   +1 more source

Availability of facilities and equipment to provide emergency care in ambulances, which transport patients to the National Hospital of Sri Lanka

Journal of the College of Community Physicians, 2019
Objective To describe available facilities and equipment in ambulances, to provide essential emergency care, which transport patients to the National Hospital of Sri Lanka Methods A descriptive cross-sectional hospital based study was carried out at the
Gangadevi Nandasena, Chrisantha Abeysena
doaj   +1 more source

Incidence and root causes of surgery cancellations at an academic medical center in Iran: a retrospective cohort study on 29,978 elective surgical cases

Patient Safety in Surgery, 2023
Introduction Canceling scheduled surgeries on the day of surgery places a heavy burden on healthcare providers and has psychological, social, and financial consequences on patients and their families.
Vida Naderi-Boldaji, Mahsa Banifatemi, Raheleh Zandi, Mohammad Hossein Eghbal, Milad Nematollahi, Mohammad Ali Sahmeddini   +5 more
doaj   +1 more source