Results 81 to 90 of about 578,184 (246)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

The Influence of Equipment Design and Process Parameters on Granule Breakage in a Semi-Continuous Fluid Bed Dryer after Continuous Twin-Screw Wet Granulation. [PDF]

Pharmaceutics, 2021
Ryckaert A, Ghijs M, Portier C, Djuric D, Funke A, Vervaet C, De Beer T.   +6 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Can gendered personal protective equipment design account for high infection rates in female healthcare workers following intubation? A reply. [PDF]

Anaesthesia, 2021
Wong DJN, El-Boghdadly K, Johnstone C, Ahmad I, intubate COVID collaborators.   +4 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Deformation analysis and hole diameter error compensation for hybrid robot based helical milling

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
As an innovative machining process for hole-making, helical milling (also known as orbital drilling) presents great potential in machining aircraft structures due to temperature and cutting force reduction, flexible kinematics, and improved borehole ...
Hao LI, Qingshan XU, Shimei WEN, Xuda QIN, Tian HUANG   +4 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Configuration Investigation, Structure Design and Deployment Dynamics of Rigid-Reflector Spaceborne Antenna with Deviation-Angle Panel

Sensors
Rigid-reflector spaceborne antennas (RRSAs) are well-suited for high-frequency application scenarios due to their high surface accuracy. However, the low stowing efficiency of RRSAs limits the aperture diameters and further deteriorates the ...
Guodong Tan, Kaiqi Liu, Xuechao Duan, Qunbiao Wang, Dan Zhang, Dongwu Yang, Dingchao Niu   +6 more
doaj   +1 more source

Identification and Adjustment of Guide Rail Geometric Errors Based on BP Neural Network

Measurement Science Review, 2017
The relative positions between the four slide blocks vary with the movement of the table due to the geometric errors of the guide rail. Consequently, the additional load on the slide blocks is increased.
He Gaiyun, Huang Can, Guo Longzhen, Sun Guangming, Zhang Dawei   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source