Results 31 to 40 of about 1,583,866 (313)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Radioisotope thermionic power supply for spacecraft [PDF]

open access: yes, 1972
Power supply design for unmanned electric propulsion missions to outer planets utilizes a store of curium-244 in compact array of capsules as energy source.
Gietzen, A. J.   +2 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Proposal and Validation of a Diagnosis Method of Fuel Failures in Pressurized Water Reactor Nuclear Power Plants

open access: yesScience and Technology of Nuclear Installations
Based on research into the diagnosis methods for fuel failures in pressurized water reactor nuclear power plants and an analysis of existing problems, this paper proposes an enhanced fuel failure diagnosis method, addressing three key improvements ...
Weifeng Lyu   +4 more
doaj   +1 more source

Chemistry laboratory safety manual available [PDF]

open access: yes, 1968
Chemistry laboratory safety manual outlines safe practices for handling hazardous chemicals and chemistry laboratory equipment. Included are discussions of chemical hazards relating to fire, health, explosion, safety equipment and procedures for certain ...
Elsbrock, R. G.
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Development of Multifunctional Detection Robot for Roller Coaster Track

open access: yesSensors, 2023
Recent advances in roller coasters accelerate the creation of complex tracks to provide stimulation and excitement for humans. As the main load-bearing component, tracks are prone to damage such as loose connecting bolts, paint peeling, corroded sleeper ...
Weike Song   +4 more
doaj   +1 more source

Health and safety in an organisation [PDF]

open access: yes, 2018
Health and Safety of employees are of utmost importance for the performance of both the employees and the organisation. The main aim of this research project is to study the health and safety issues existing within an organisation.
Sharma, Chirag, Wood, Brent
core  

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Generalized safety equation - A concept [PDF]

open access: yes, 1971
Concept provides definition of relationship between safety and reliability, personnel safety measurement, and equipment safety evaluation. Safety systems cope with single or combined risks.
Hano, G.
core   +1 more source

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