Results 51 to 60 of about 1,618,905 (354)

Silicon carbide equipments for process intensification of silicon reactions. [PDF]

open access: yes, 2009
Bluestar Silicones, one of the worldwide leaders in silicones chemistry, proposes a R&D project, aiming to design new equipment for the transposition of batch to continuous processes. The safety and environmental issues linked to this type of chemicals,
Elgue, Sébastien   +5 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Modern weapons and military equipments for issue 3-2019 / Современное вооружение и военное оборудование, к выпуску № 3-2019 / Savremeno naoružanje i vojna oprema za broj 3-2019 [PDF]

open access: yesVojnotehnički Glasnik, 2019
Russia Has Tested Its Tsirkon Hypersonic Missile "Over Ten Test Launches"; Russian Forces are Adding a Silent-but-Deadly New Weapon to Their Arsenal; This Submarine Is "Invincible": Meet the Super Sub Headed to China's Doorstep; Russia Is Arming Its ...
Dragan M. Vučković
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Modern weapons and military equipments for issue 2-2019 / Современное вооружение и военное оборудование, к выпуску № 2-2019 / Savremeno naoružanje i vojna oprema za broj 2-2019 [PDF]

open access: yesVojnotehnički Glasnik, 2019
Analysis: Top 15 most modern main battle tanks MBTs in the world / Анализ: 15 самых современных основных боевых танков в мире / Analiza: 15 najmodernijih osnovnih borbenih tenkova u ...
Dragan M. Vučković
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Savremeno naoružanje i vojna oprema za broj 1-2022

open access: yesVojnotehnički Glasnik, 2022
Osnovni borbeni tenk T-80BVM ulazi u službu na ...
Dragan M. Vučković
doaj  

Research and innovation in power electronics systems applied to energy management [PDF]

open access: yes, 2008
The Power Electronics Systems Group (GSEP) at University Carlos III de Madrid (Spain) offers its wide experience and background in consultancy, R&D projects with private and public funding and pre-industrial prototype building in four main topics: energy
Barrado Bautista, Andrés
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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