Results 81 to 90 of about 59,942 (247)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Modern weapons and military equipments for issue 3-2017 / Современное вооружение и военное оборудование, к выпуску № 3-2017 / Savremeno naoružanje i vojna oprema za broj 3-2017

Vojnotehnički Glasnik, 2017
Wireless Technology Brings Crosshair from Thermal Sights to Night Vision Goggle Display; More bang for Bundeswer behemonts; The F-35 Stealth Fighter May Never Be Ready for Combat.
Dragan M. Vučković
doaj   +2 more sources

Analysis on milling stability of fuel tank's bottom combined with surface location error prediction

International Journal of Lightweight Materials and Manufacture, 2019
The bottom of fuel tank is a lightweight thin-walled part with large size and complex surfaces. Its processing quality directly determines the reliability of the whole rocket.
Fan Qiao, Fei Ren, Xiao Liu
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Design of inspection system for coal mine equipments based on RFID

, 2018
In view of problems of many hidden dangers and weak electromechanical technology of coal mine equipments management, an inspection system for coal mine equipment based on RFID was designed.
HAN An, CUI Xiguo
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Savremeno naoružanje i vojna oprema za broj 1-2024

Vojnotehnički Glasnik
Јапански електромагнетни шински топ средњег калибра; Граната за артиљеријско оруђе са набојно-млазним мотором; Нови детаљи у вези бомбардера B-21; E-7A Wedgetail AEW&C замена за стари E-3 ...
Dragan M. Vučković
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Modern weapons and military equipments for issue 3-2020 / Современное вооружение и военное оборудование, к выпуску № 3-2020 / Savremeno naoružanje i vojna oprema za broj 3-2020

Vojnotehnički Glasnik, 2020
Modernization of the Moscow anti-missile shield; Turkey chooses Ukrainian active protection system Zaslon; New Swedish submarine; Firefly: Israeli "wandering" ammunition (or kamikaze drone); The MZ-204 Highlander mortar prototype is ready; Operation ...
Dragan M. Vučković
doaj