Results 51 to 60 of about 819,494 (303)

A national perspective on exposure to essential surgical procedures among medical trainees in Nigeria: a cross-sectional survey and recommendations

BMC Medical Education, 2023
Background In sub-Saharan Africa, recent graduates from medical school provide more direct surgical and procedural care to patients than their counterparts from the Global North.
Paul Tunde KingPriest, Barnabas Tobi Alayande, Emmanuel Walong Clement, Mustapha Muhammed, Joy Ohejem Egbiri, Miracle Shanabo, Etinosa Kevin Osayande, Abiodun Ayomide Atunrase, Jamiu Israel Abubakar, Daniel Chukwuma Eze, Stephen Adekoya, Gideon Bulus Chiroma, Onosegbe Moses Aikhuomogbe, Fatima Shuwa Gaila, Dennis Yaga, Nomsu Noble Thomas, Chukwudi Anthony Chukwunta, Matthew T. Hey, Callum Forbes, Robert R. Riviello, Bashiru O. Ismaila   +20 more
doaj   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Barriers to contraceptive access and use among youths (15–24 Years) living in informal urban settlements of Kigali, Rwanda: a qualitative study

Discover Public Health
Background Contraceptive use among youths below 19 years in Rwanda is still very low, as low as 3.7%, yet their level of sexual activity is high. By 2020, 42% and 31% of women and men respectively had initiated sex before the age of 20 years.
Emmanuel Okiror Okello, Alexandre Edgard Murinzi, Colyse Nduwimana, Rashidah Nambaziira   +3 more
doaj   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

“An eye-opener:” a qualitative study of a liberal arts approach to medical education

BMC Medical Education
Background Medical educators have underscored the need for medical students to study the larger sociocultural and economic forces that influence health rather than simply basic and clinical sciences; however, previous studies have not evaluated the ...
Abebe Bekele, Denis Regnier, Claire O. Swedberg, Eden Abate Lemu, Christelle Uwantege Giraneza, Elizabeth H. Bradley   +5 more
doaj   +1 more source

Tools and approaches to operationalize the commitment to equity, gender and human rights: towards leaving no one behind in the Sustainable Development Goals

Global Health Action, 2018
The objective of this article is to present specific resources developed by the World Health Organization on equity, gender and human rights in order to support Member States in operationalizing their commitment to leave no one behind in the health ...
Gerardo Zamora, Theadora Swift Koller, Rebekah Thomas, Mary Manandhar, Eva Lustigova, Adama Diop, Veronica Magar   +6 more
doaj   +1 more source

Addressing the mental health needs of children affected by HIV in Rwanda: validation of a rapid depression screening tool for children 7–14 years old

BMC Pediatrics, 2021
Background Depression in children presents a significant health burden to society and often co-exists with chronic illnesses, such as human immunodeficiency virus (HIV).
Agnes Binagwaho, Eric Remera, Alice Uwase Bayingana, Darius Gishoma, Kirstin Woody Scott, Madeline Goosman, Eliza Campbell, Mawuena Agbonyitor, Yvonne Kayiteshonga, Sabin Nsanzimana   +9 more
doaj   +1 more source

Improving the Odds: Increasing Opportunities in Austin [PDF]

, 2001
The City of Austin has a history of attempting to address equity, starting with the Austin Equity Commission, led by Chair Ray Marshall, which delivered a report in 2001 titled, “Improving the Odds: Increasing Opportunities in Austin.”3 The Austin ...
Austin Equity Commission
core   +1 more source

Dipolar Coupling Errors in Nuclear Spin Qubits

Advanced Science, EarlyView.
Multi‐nuclear spin registers of phosphorus‐atom qubits in silicon have demonstrated 99.99% single and >$>$99.9% two qubit gate fidelities. Despite nanometer separation, read‐out fidelities between individual nuclear spins within the register are not identical.
I. D. Thorvaldson, P. Macha, J. Reiner, S. H. Misha, Y. Chung, L. Kranz, D. Keith, S. Monir, D. Poulos, S. Sutherland, Y.‐L. Hsueh, B. Thorgrimsson, R. Rahman, J. G. Keizer, S. K. Gorman, M. Y. Simmons   +15 more
wiley   +1 more source

Resilience and coping strategies of older adults in Hong Kong during COVID-19 pandemic: a mixed methods study

BMC Geriatrics, 2022
Background Despite the adverse physical health impact of COVID-19 on older adults, whether they are psychosocially vulnerable under the pandemic remains debatable.
Siu-Ming Chan, Gary Ka-Ki Chung, Yat-Hang Chan, Roger Yat-Nork Chung, Hung Wong, Eng Kiong Yeoh, Jean Woo   +6 more
doaj   +1 more source