Results 91 to 100 of about 1,262,397 (358)

An Optimal Fuzzy PID Controller Design Based on Conventional PID Control and Nonlinear Factors

open access: yesApplied Sciences, 2019
This paper proposes an optimal fuzzy proportional–integral–derivative (PID) controller design based on conventional PID control and nonlinear factors.
Chun-Tang Chao   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Long-term outcomes in chronic obstructive pulmonary disease patients: exploring the effects of inhalatory devices and their influence on the outcome

open access: yesClinicoEconomics and Outcomes Research, 2016
Valeria Fadda, Dario Maratea Department of Pharmaceutical Sciences, University of Florence, Sesto Fiorentino, FI, Italy Purpose: Numerous systematic reviews have examined the outcomes in patients with chronic obstructive pulmonary disease managed with ...
Fadda V, Maratea D
doaj  

From Equality to Equivalence?: 'Norwegian health policies towards immigrants and the Sámi, 1970–2009'

open access: yesNordic Journal of Migration Research, 2013
This article investigates a shift in the justifying ideas in Norwegian public health and immigrant policies. Between 1970 and 2009, equality was gradually supplanted with equivalence as the main principle evoked in policy formulation.
Teemu Ryymin, Kari Ludvigsen
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The Trans-Atlantic Trade and Investment Partnership – A Challenge for the European Union? [PDF]

open access: yesRomanian Journal of European Affairs, 2015
Since the early 2000s, the United States and European Union have discussed the development of bilateral and regional trade agreements. The TTIP – Trans-Atlantic Trade and Investment Partnership was announced in February 2013 and is currently under ...
Oana–Antonia Colibășanu   +1 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Epistemic Information in Stratified M-Spaces

open access: yesInformation, 2011
Information is usually related to knowledge. However, the recent development of information theory demonstrated that information is a much broader concept, being actually present in and virtually related to everything. As a result, many unknown types and
Mark Burgin
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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