Results 61 to 70 of about 6,656 (189)

Industrial Experiences with a Formal DSL Semantics to Check the Correctness of DSL Artifacts [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
A domain specific language (DSL) abstracts from implementation details and is aligned with the way domain experts reason about a software component.
Sarmen Keshishzadeh   +2 more
doaj   +1 more source

Expression equivalence checking using interval analysis [PDF]

open access: yesIEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2006
Arithmetic expressions are the fundamental building blocks of hardware and software systems. An important problem in computational theory is to decide if two arithmetic expressions are equivalent. However, the general problem of equivalence checking, in digital computers, belongs to the NP Hard class of problems.
Ghodrat, Mohammad Ali   +2 more
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Concurrent software fine‐coarse‐grained automatic modelling by Coloured Petri Nets for model checking

open access: yesIET Software, 2023
The state space explosion restricts the error detection of concurrent software. The abstraction can provide a solution to avoid state space explosion, but it is easy to ignore important details, resulting in inaccurate detection results.
Wenjie Zhong, Jian‐tao Zhou, Tao Sun
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Logical Characterization of Trace Metrics [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2017
In this paper we continue our research line on logical characterizations of behavioral metrics obtained from the definition of a metric over the set of logical properties of interest.
Valentina Castiglioni, Simone Tini
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

On the application of substitution algebra to program unification

open access: yesТруды Института системного программирования РАН, 2018
Many problems in software engineering such as program refactoring, deobfuscation, vulnerability detection, require an efficient toolset for detecting pieces of code that have similar behavior.
V. A. Zakharov, T. A. Novikova
doaj  

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