Results 161 to 170 of about 166,055,931 (301)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Validation of the Italian version of the In-Person Telephone Interview for Cognitive Status (IP-TICS). [PDF]

Neurol Sci
Aiello EN, Guidetti E, De Luca G, Frisco F, Curti B, Moreschi A, Esposti L, Casartelli S, Curatoli C, Zanin A, Camporeale E, Sirtori MA, Verde F, Silani V, Ticozzi N, Poletti B, Bolognini N.   +16 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Measurement Equivalence of Diabetes Self-Management, Distress, and Quality-of-Life Measures in Adults with Type 2 Diabetes in Vietnam. [PDF]

Nurs Rep
Nguyen TT, Vo HT, Nguyen TTV, Son PM, Xim VT, Pham TMN, Phan MA, Nguyen TA.   +7 more
europepmc   +1 more source

Stimulus equivalence and supplemental measures on equivalence relations

, 2012
The present article introduces stimulus equivalence research as an experimental analysis on how previously unrelated stimuli can generate a specific pattern of responding without being directly taught. Murray Sidman and colleagues set forth that stimulus equivalence should be considered as a basic process in line with other behavioral processes such as
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Equivalence Scales Based on Revealed Preference Consumption Expenditure Microdata - The Case of West Germany zu Lüneburg [PDF]

Equivalence scales are a prerequisite for any economic well-being comparison with measures on income distribution, inequality and poverty. This paper provides equivalence scales based on revealed preference consumption microdata for West Germany 1983. It
Joachim Merz, Jürgen Faik
core  

Towards cultural validation of the revised children's anxiety and depression scale in Karnataka, India: Think aloud interviews among 13-17 year olds. [PDF]

PLoS One
Palmer A, O'Connor DB, Bhola P, Khandeparkar P, Janardhana N, Prabhu S, A L K, Arelingaiah M, K P J, Nag R, Hugh-Jones S.   +10 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Translation and cross-cultural adaptation of the parental version of Type 1 Diabetes and Life (T1DAL): a US patient-reported outcome measurement into Danish following ISPOR guidelines. [PDF]

BMJ Open
Lind N, DeCosta P, Svensson J.
europepmc   +1 more source