Results 31 to 40 of about 64,751 (216)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Equivalent Electrical Circuits of Thermoelectric Generators under Different Operating Conditions

Energies, 2017
Energy harvesting has become a promising and alternative solution to conventional energy generation patterns to overcome the problem of supplying autonomous electrical systems.
Saima Siouane, Slaviša Jovanović, Philippe Poure   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient Equivalent Circuits Model for Electric-LC Resonators in Periodic and Closed Waveguides

IEEE Access
This paper details the extraction of possible equivalent circuits over a wide band for an Electric-LC resonator in two technological configurations: a) a multilayer stack working at mm-wave and b) a WR90 waveguide in the X band.
C. H. Joseph, D. Mencarelli, L. Pierantoni, P. Russo, L. Zappelli   +4 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Equivalent Electrical Circuits and Their Use Across Electrochemical Impedance Spectroscopy Application Domains

IEEE Access, 2022
When studying electrochemical systems, EIS practitioners face the challenge of choosing a relevant equivalent electrical circuit to analyze their measurement data and interpreting the role of its components.
Maxime Van Haeverbeke, Michiel Stock, Bernard De Baets   +2 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Fractional Diffusion Equations and Equivalent Circuits Applied to Ionic Solutions

International Journal of Electrochemical Science, 2014
We investigate dilute solutions of different salts (KClO3, K2SO4, and CdCl2H2O) dissolved in Milli-Q deionized water in the context of the fractional diffusion equations and equivalent circuits.
F.R.G.B. Silva, H.V. Ribeiro, M.K. Lenzi, T. Petrucci, F.S. Michels, E.K. Lenzi   +5 more
doaj   +1 more source