Results 121 to 130 of about 4,496,022 (300)

The Business Studies University: Turning higher education into further education

open access: yesLondon Review of Education, 2016
This paper argues that changes to both further and higher education that are already well underway are clarified by what can be called the model of the Business Studies University (BSU).
doaj   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Research on Distributed Magnetic Circuit for Rail-type ICPT System With High Energy-efficiency Character

open access: yes工程科学与技术, 2012
:According to the drawbacks of the traditional rail-type inductively coupled power transfer (ICPT) system, which mainly improves its output power and efficiency by increasing the input voltage or the capacity of the magnetic core, a new distributed ...
Xia Chen-yang
doaj  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

STUDY ON NEED FOR SUSTAINABLE DEVELOPMENT IN EDUCATIONAL INSTITUTIONS, AN ECOLOGICAL PERSPECTIVE - A CASE STUDY OF COLLEGE OF ENGINEERING - GUINDY, CHENNAI

open access: yesJournal of Urban and Environmental Engineering, 2010
Sustainability has become the key word of developing world and it¿s evident in many issues, the growing economy is facing nowadays. Sustainability is the need of the hour for Indian economy to support our future generation with a cleaner, safer ...
Gobinath Ravindran, R. Nagendran
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Prompt-Based Cognitive Equivalence Theory: Toward a Post-Institutional Future of Knowledge Excellence

open access: yes
Prompt-Based Cognitive Equivalence Theory (PB-CET) introduces a novel learning paradigm that empowers students from under-resourced institutions to achieve epistemic parity with elite academic thinkers. This theory argues that through carefully structured, recursive, and dialogic prompt design using generative AI tools like ChatGPT, learners can ...
openaire   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

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