Results 41 to 50 of about 1,110,603 (243)

Theoretical backgrounds of durability analysis by normalized equivalent stress functionals [PDF]

, 2003
Generalized durability diagrams and their properties are considered for a material under a multiaxial loading given by an arbitrary function of time. Material strength and durability under such loading are described in terms of durability, safety factor ...
Bolotin, V. V., Hoff, N. J., Il’ushin, A. A., Kachanov, L. M., Mikhailov, S. E., Mikhailov, S. E., Nikiforovsky, V. S., Nikiforovsky, V. S., Penny, R. K., Rabotnov, Yu. N., Rabotnov, Yu. N., Robinson, E. L., Robinson, E. L., S. E. Mikhailov   +13 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Functionally graded thick-walled tubes analysis by numerical methods

Heliyon
Functionally graded materials are increasingly used in the practice of engineering design, as is the case with thick-walled tubes. The use of these constructive elements requires a calculation, which should be as accurate, as accessible and as fast as ...
Vasile Nastasescu, Silvia Marzavan
doaj   +1 more source

Numerical Investigation of the Influence of Pulsed Laser Deposited Tin Thin Film Morphology on Deformation Inhomogeneities [PDF]

Archives of Metallurgy and Materials, 2020
Investigation of influence of TiN thin film morphology on deformation inhomogeneities is an overall subject of the research. Numerical modelling approach that was selected for the study is based on the digital material representation concept, which gives
K. Perzyński, D. Zych, M. Sitko, Ł. Madej   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Light enough or go lighter?

Materials & Design, 2019
A novel concept for evaluating the lightweight design of structural components, named the true lightweight degree, is developed. It is found that traditional lightweight parameters just constitute a lower bound for stiffness-oriented designs. This can be
Marlon Hahn, Soeren Gies, A. Erman Tekkaya   +2 more
doaj   +1 more source

Equivalent Morphology Concept in Composite Materials Using Machine Learning and Genetic Algorithm Coupling

Journal of Composites Science
The objective of this study is to investigate the synergistic integration of machine learning and evolutionary algorithms for the discovery of equivalent morphologies exhibiting analogous behavior within the domain of composite materials. To pursue this objective, two comprehensive databases are meticulously constructed.
Beji, Hamdi, Messager, Tanguy, Kanit, Toufik   +2 more
openaire   +2 more sources

Ductile Failure Prediction of U-Notched Bainitic Functionally Graded Steel Specimens Using the Equivalent Material Concept Combined with the Averaged Strain Energy Density Criterion [PDF]

Physical Mesomechanics, 2019
В статье изучено вязкое разрушение функционально-градиентной бейнитной стали. Испытания на разрушение проводили с использованием образцов с U-образным надрезом из функционально-градиентной бейнитной стали при нагружении типа I. Оценку вязкого разрушения образцов проводили с использованием критерия усредненной плотности энергии деформации и концепции ...
Salavati, Hadi, Mohammadi, Hossein
openaire   +3 more sources

The nonlinear time-dependent response of isotactic polypropylene

, 2002
Tensile creep tests, tensile relaxation tests and a tensile test with a constant rate of strain are performed on injection-molded isotactic polypropylene at room temperature in the vicinity of the yield point. A constitutive model is derived for the time-
Aboulfaraj M., Aleksey D. Drozdov, Ariyama T., Ariyama T., Bergström J. S., Boyce M. C., Coulon G., Drozdov A. D., Drozdov A. D., Duan Y., Dutta N. K., Eyring H., Fayolle B., G’Sell C., Haward R. N., Iijima M., Jesper deC. Christiansen, Kalay G., Krempl E., Losi G. U., Lustig S. R., Maiti P., Meyer R. W., Nitta K.-H., Nitta K.-H., Read B. E., Seguela R., Smart J., Staniek E., Sweeney J., Sweeney J., Sweeney J., Tomlins P. E., Verma R., Ward I. M., Wineman A. S., Wortmann F.-J., Zhang X. C.   +37 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source