Results 41 to 50 of about 9,446,010 (274)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Static assessment of plain/notched polylactide (PLA) 3D‐printed with different infill levels: Equivalent homogenised material concept and Theory of Critical Distances [PDF]
Fatigue & Fracture of Engineering Materials & Structures, 2018 AbstractA novel approach based on the equivalent homogenised material concept and the theory of critical distances is formulated to perform static assessment of plain/notched objects of polylactide (PLA) when this polymer is additively manufactured with different infill levels.
Adnan A. Ahmed, Luca Susmel
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A novel sandwich panel made of prepreg flax skins and bamboo core
Composites Part C: Open Access, 2020 This work describes the bending and shear mechanical properties of a novel concept of sustainable sandwich panel made from unidirectional prepreg flaxtape skins and bamboo rings as a circular core material.
Lívia Ávila de Oliveira +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Concept Journal Vol. 4 No. 3 Winter 2013 Full Issue
, 2013 Concept full ...
Full Issue, Concept
core +1 more source
Materials & Design, 2019 A novel concept for evaluating the lightweight design of structural components, named the true lightweight degree, is developed. It is found that traditional lightweight parameters just constitute a lower bound for stiffness-oriented designs. This can be
Marlon Hahn +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Celebrating 25 Years of Concept: The First Issue, Autum 1990
, 2015 This is the first every copy of concept, autum 1990.
Editorial Board, Concept
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source