Results 11 to 20 of about 336,542 (173)

A method for determining material's equivalent stress-strain curve with any axisymmetric notched tensile specimens without Bridgman correction [PDF]

open access: yesInternational Journal of Mechanical Sciences, 2018
Abstract Large deformation analyses of problems such as plastic forming, ductile fracture with finite element method need a full range of material's equivalent stress-strain curve or flow stress-strain curve. The equivalent stress-strain curve determined from the smooth round bar specimen should be corrected after diffuse necking, since tri-axial ...
Shengwen Tu   +3 more
openaire   +5 more sources

Welding deformation analysis based on improved equivalent strain method considering the effect of temperature gradients

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2015
ABSTRACT:In the present study, the existing equivalent stain method is improved to make up for its weaknesses. The improved inherent strain model is built considering more sophisticated three dimensional constraints which are embodied by six cubic elements attached on three sides of a core cubic element.
Kim, Tae-Jun   +2 more
openaire   +5 more sources

Friction Stir Welding Analysis Based on Equivalent Strain Method using Neural Networks

open access: yesJournal of Ocean Engineering and Technology, 2014
The application of friction stir welding (FSW) technology has been extended to all industries, including shipbuilding. A heat transfer analysis evaluates the weldability of a welded work piece, and elasto-plastic analysis predicts the residual stress and deformation after welding.
Sung-Wook Kang, Beom-Seon Jang
openaire   +4 more sources

A refined method for determining equivalent radius (Req) in resonant column tests across a wide strain range

open access: yesInternational Journal of Geo-Engineering
Abstract The equivalent radius $$\:{R}_{eq}$$ has been used for calculation of strain in Resonant Column (RC) testing. Present calculation methods for $$\:{R}_{eq}$$
Tien Hue Nguyen, Taebong Ahn, Yujin Lim
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

A Novel Method to Describe Large-Range Stress-Strain Relations of Elastic-Plastic Materials Based on Energy Equivalence Principle

open access: yesMaterials, 2023
Due to the unique structure of tensile sheet specimens with a circular hole (CHS specimen), a novel method is proposed to predict the large-range uniaxial stress-strain relations of elastic-plastic materials analytically. Based on the energy equivalence principle, a load-displacement semi-analytical model of the CHS specimen is proposed.
Simiao Yu   +3 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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