Results 171 to 180 of about 233,296 (308)

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Efficacy of Vonoprazan-Doxycycline Dual Therapy for the Treatment of <i>Helicobacter pylori</i> Infection: A Retrospective Cohort Study. [PDF]

Infect Drug Resist
Zhang X, Li Q, Deng Y, Zhang X, Xin R, Yang T, Guo X, Ma X, Li X, Tang Y, Guo R, Ma L, Hou Z, Wang J, Hou N, Hu S.   +15 more
europepmc   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

Early population-level impact of Helicobacter pylori eradication on gastric cancer mortality in Japan: a counterfactual analysis of short-term divergence. [PDF]

Popul Health Metr
Kowada A.
europepmc   +1 more source

Bangladesh Smallpox Eradication Programme documentation for international commission status report, June 1, 1976

WHO has established a two year period of zero cases as the prime criteria for certification of smallpox eradication. At the end of the two years (November 1977) an International Commission will come to Bangladesh.

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Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Evidence-Based Guidelines for the Diagnosis and Treatment of Helicobacter pylori Infection in Korea: 2025 Revised Edition. [PDF]

Korean J Helicobacter Up Gastrointest Res
Bang CS, Kang SJ, Lim H, Kim SH, Lee MW, Nam SY, Tae CH, Kim SE, Kim SY, Jung HK, Kim BJ, Choi M, Jung HY, Kim BW, Korean College of Helicobacter and Upper Gastrointestinal Research.   +14 more
europepmc   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

A Case of Localized Gastric Amyloidosis With Improvement on Endoscopy After Eradication of Helicobacter pylori. [PDF]

Korean J Helicobacter Up Gastrointest Res
Lim NR, Shin D, Chung WC.
europepmc   +1 more source

Entomological handbook for Aedes aegypti eradication [PDF]

"Eradication of an insect from a large geographical area is a most difficult entomological accomplishment. Moderately effective measures often suffice to reduce insect populations to an inoffensive level, but eradication requires a sharpening and ...

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