Results 81 to 90 of about 233,296 (308)
The eradication of gonorrhoea [PDF]
BMJ, 1994 The continued global survival of Neisseria gonorrhoeae is inevitable because of its immunobiology,1 the seeming lack of natural or acquired immunity, human sexual behaviour, and the frequency of asymptomatic infection. Nevertheless, endemic gonorrhoea could be eradicated from Britain in the 1990s.
openaire +2 more sources
Advanced Science, EarlyView.High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott +5 more
wiley +1 more source
Viruses, 2020 Modern antiretroviral therapy for immunodeficiency viruses, although remarkably effective in controlling viral transcription, and overt virus-associated morbidity, has failed to absolutely eradicate retroviruses from their infected hosts as a result of ...
Brian G. Murphy +4 more
doaj +1 more source
Advanced Science, EarlyView.Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source
Government Financial Management, Strategy for Preventing Corruption in Indonesia
The South East Asian Journal of Management, 2007 In popular view, the term accountability generally refers to a wide spectrum of public expectations dealing with organizational performance, responsiveness, good governance, and even morality of government and nonprofit organizations.
Haryono Umar
doaj
Advanced Science, EarlyView.MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou +21 more
wiley +1 more source
Global Polio Eradication Initiative; strategic plan, 2004-2008 [PDF]
By end-2003, poliomyelitis had been eliminated from all but 6 countries in the world as a result of the Global Polio Eradication Initiative, the largest international public health effort to date. Nearly 5 million children are walking who would otherwise
core
Value of investing in neglected tropical diseases : an investment case for the elimination and eradication of onchocerciasis (river blindness) [PDF]
, 2015 Elimination of neglected tropical diseases (NTDs) has emerged on the global agenda. This PhD research developed an investment case for the elimination and eradication of onchocerciasis (river blindness) which is one of the NTDs endemic in Africa.
Kim, Young Eun
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Advanced Science, EarlyView.A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source
Control, elimination, and eradication of river blindness: scenarios, timelines, and ivermectin treatment needs in Africa [PDF]
, 2015 River blindness (onchocerciasis) causes severe itching, skin lesions, and vision impairment including blindness. More than 99% of all current cases are found in sub-Saharan Africa.
Remme, JHF +31 more
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