Results 191 to 200 of about 171,809 (260)

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

Angewandte Chemie, EarlyView.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang, Xiaolan Yin, Jeongyeon Hong, Qixian Chen, Weijie Chi, Jingyun Wang, Juyoung Yoon, Haidong Li   +7 more
wiley   +2 more sources

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Engineering BN‐Doped Open‐Shell Polycyclic Hydrocarbons for Enhanced Photothermal Conversion and Therapy

Angewandte Chemie, EarlyView.
Two novel bonded BN‐doped polycyclic hydrocarbons BN‐Dira and BN‐Tetra with open‐shell character were rationally designed and synthesized. Their molecular structures were unambiguously confirmed by crystallographic analysis. Facilitated by their intense absorption in the NIR region, high PCE (83.6%) and good photothermal stability, BN‐Dira and BN‐Tetra
Peiyun Zeng, Ziqi Zhuang, Huan Luo, Yubin Fu, Peiyu Wang, Yating Zheng, Gang Liu, Junzhi Liu   +7 more
wiley   +2 more sources

Tailored screening and eradication of <i>Helicobacter pylori</i> at a subnational level of China: multicenter observational studies in Ya'an city and a rapid meta-analysis in Sichuan province. [PDF]

Front Public Health
Wang L, Chen O, Chen XZ, SIGES Research Group.   +3 more
europepmc   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Persistence of <i>Helicobacter pylori</i> Infection Despite Therapy: Eight-Year Real-World Experience from a Saudi Tertiary Center. [PDF]

J Clin Med
Alassaf Y, Aleid S, Alenezi F, Alhabs G, Almutairi T, Alsalamah S, Althabit N, Alshabeer S, Almohaya A, Albabtain M, Bosaeed M.   +10 more
europepmc   +1 more source

Maternal antibody-mediated elimination of a Puumala hantavirus outbreak in a bank vole colony. [PDF]

PLoS Pathog
Drewes S, Wyszkowska J, Jaromin E, Hajduk J, Onik I, Konczal M, Lach K, Bober-Sowa B, Baliga-Klimczyk K, Sadowska ET, Ulrich RG, Koteja P.   +11 more
europepmc   +1 more source

Vonoprazan-Amoxicillin Dual Therapy with or Without <i>Saccharomyces boulardii</i> Supplementation as a Rescue Regimen for <i>Helicobacter pylori</i> Infection. [PDF]

Infect Drug Resist
Qu DN, Ji ZX, Zhang JQ, Wang XY.
europepmc   +1 more source

A Review on the Progress and Strategies of <i>Helicobacter pylori</i> Eradication Therapy for Patients With Penicillin Allergy. [PDF]

Gastroenterol Res Pract
Zhang Y, Suo B, Tian X, Li C, Ren X, Zhou K, Mi C, Wang Y, Ma L, Zhou L, Song Z.   +10 more
europepmc   +1 more source

Gastric Cancer-Associated Immunomodulatory Fibroblasts Persist Following Helicobacter pylori Eradication: The Need to Douse a Smoldering Fire. [PDF]

Cell Mol Gastroenterol Hepatol
Noto JM, Peek RM.
europepmc   +1 more source