Results 131 to 140 of about 103,457 (262)
Polio: abandoning eradication would result in rapid resurgence of an ancient scourge
BMJ Global Health, 2019 Roland Walter Sutter +1 more
doaj +1 more source
Advanced Science, EarlyView.The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
Towards the eradication of hepatitis B in Taiwan
, 2014 Viral hepatitides are important public health problems in humans. The etiologic agents were not identified until 1965, when Baruch S. Blumberg found the relationship of Australia antigen to serum hepatitis. The antigen was found to be the surface antigen
Wait, Suzanne;Chen, Ding-Shinn +1 more
core +1 more source
eLifeLarge reductions in the global malaria burden have been achieved, but plateauing funding poses a challenge for progressing towards the ultimate goal of malaria eradication.
Nora Schmit +7 more
doaj +1 more source
Advanced Science, EarlyView.Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han +11 more
wiley +1 more source
Polio eradication strategy 2022\u20132026 : delivering on a promise [French]
Polio eradication strategy 2022\u20132026 : delivering on a promise [French]9789240035300-fre ...
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Winners and losers from Johne’s disease eradication from the Scottish dairy herd: a Markov-Chain simulation [PDF]
In this paper, we evaluated the welfare effects of a hypothetical programme of Johne's disease eradication from the Scottish dairy herd on different stakeholders in the domestic milk market. We undertook the evaluation using a Markov-Chain simulation and
Weldegebriel, Habtu T. +2 more
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Advanced Science, EarlyView.This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang +11 more
wiley +1 more source
Polio eradication and endgame strategic plan 2013-2018
Since its launch at the World Health Assembly (WHA) in 1988, the Global Polio Eradication Initiative (GPEI) has reduced the global incidence of polio by more than 99% and the number of countries with endemic polio from 125 to 3.
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