Results 161 to 170 of about 103,457 (262)
Advanced Science, EarlyView.Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie +10 more
wiley +1 more source
WHO has established a two year period of zero cases as the prime criteria for certification of smallpox eradication. At the end of the two years (November 1977) an International Commission will come to Bangladesh.
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Unsung heroes of polio eradication [PDF]
As long as polio exists anywhere, it is a threat to children everywhere.Facts about the polio vaccineIn 1955, the polio vaccine is licensed for use, and the first vaccination campaigns begin.In 1988, polio cases worldwide 125 countries = 350,000 ...
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Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Global Polio Eradication progress 1999 [PDF]
The global initiative to eradicate polio by the end of 2000 has become the largest public health initiative in history, and is spearheaded by WHO, Rotary International, U.S. Centers for Disease Control and Prevention, and UNICEF.
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Advanced Science, EarlyView.Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
Entomological handbook for Aedes aegypti eradication [PDF]
"Eradication of an insect from a large geographical area is a most difficult entomological accomplishment. Moderately effective measures often suffice to reduce insect populations to an inoffensive level, but eradication requires a sharpening and ...
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Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs
Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley +1 more source
Advanced Science, EarlyView.A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou +9 more
wiley +1 more source
The Aedes aegypti Eradication Program [PDF]
Introduction -- History -- -- How the program works -- Organization -- Field operations -- Working with the community -- -- The program thus far -- Special problems -- Research.Two years ago the Public Health Service began a program to eradicate Aedes ...
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