Results 81 to 90 of about 172,128 (262)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Poliovirus serological assay after the cVDPV1 outbreak in Papua New Guinea: a cross-sectional study from 2020 to 2021Research in context

The Lancet Regional Health. Western Pacific
Summary: Background: In June 2018, a type 1 circulating vaccine-derived poliovirus (cVDPV1) outbreak was declared in Papua New Guinea (PNG), resulting in a total of 26 paralytic confirmed cases.
William Pomat, Rocio Lopez Cavestany, Visalakshi Jeyaseelan, Rebecca Ford, Janet Gare, Tigran Avagyan, Varja Grabovac, Deborah Bettels, Dessie Mekonnen, Kathryn Ann Vetter Jones, Bernardo Alfredo Mainou, Ondrej Mach   +11 more
doaj   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

The palm weevil Rhynchophorus vulneratus is eradicated from Laguna Beach

California Agriculture, 2016
In October 2010, Rhynchophorus vulneratus, originally identified as the red palm weevil, R. ferrugineus, was discovered infesting Canary Island date palms in Laguna Beach, California.
Mark S. Hoddle, Christina D. Hoddle, Mohammed Alzubaidy, John Kabashima, J. Nicholas Nisson, Jocelyn Millar, Monica Dimson   +6 more
doaj   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Commentary: Elimination of Guinea Worm Disease in South Sudan through multi-disciplinary actions

South Sudan Medical Journal, 2018
South Sudan is now in the pre-certification phase, having gone over sixteen months as of April 2018, with zero reports for cases of Guinea worm disease (GWD).
Makoy S. Yibi
doaj  

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

Advanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding, Wei Yang, Wenzhao Li, Guifang Xu, Yuanjin Zhao   +4 more
wiley   +1 more source

Investigating the dynamics of S. Enteritidis serotype spread in breeder poultry company using a whole genome sequencing approach

Frontiers in Veterinary Science
Salmonella is a globally prevalent foodborne zoonotic pathogen, with poultry and its products serving as the primary epidemiological reservoirs. As a core upstream component of the poultry industry chain, breeder farms can harbor Salmonella that ...
Qian Wang, Mengze Song, Wei Zhao, Xiaoran Hu, Zhipeng Tang, Longzong Guo   +5 more
doaj   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Inactivated Poliovirus Vaccine: Recent Developments and the Tortuous Path to Global Acceptance

Pathogens
Inactivated poliovirus vaccine (IPV), available since 1955, became the first vaccine to be used to protect against poliomyelitis. While the immunogenicity of IPV to prevent paralytic poliomyelitis continues to be irrefutable, its requirement for strong ...
Roland W. Sutter, Martin Eisenhawer, Natalia A. Molodecky, Harish Verma, Hiromasa Okayasu   +4 more
doaj   +1 more source