Results 251 to 260 of about 516,154 (332)

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Helicobacter pylori eradication rate following first line non-bismuth quadruple therapy regimen in Tunisian patients: the HPERAD study. [PDF]

BMC Infect Dis
Fekih M, Jomni T, Ayari M, Battikh H, Zribi M, Labidi A, Serghini M, Ben Zid N, Hafi M, Boubaker J, Nciri A, Ben Abdelwahed M, Zakhama M, Loghmari MH, Baklouti R, Guediche A, Bouhlel W, Jemni I, Sabbek A, Chaabene NB, Safer L, Haddad O, Kadri Y, Rhim H, Mastouri M, Belhadj Mabrouk E, Mensi A, Ayadi S, Zaimi Y, Said Y, Mouelhi L, Debbeche R, Kchaou M, Haddad W, Chtourou L, Chabchoub H, Turki M, Njeh M, Mzid A, Medjahed N, Mnif B, Hammami A, Abdallah HB, Mohamed G, Abdelli N, Abdelaali I, Douggui MH, Medhioub M, Khsiba A, Mahmoudi M, Mohamed AB, Yakoubi M, Hamzaoui L, Azzouz MM, Bibani N, Trad D, Sabbah M, Jlassi H, Elloumi H, Gargouri D, Bouchabou B, Nakhli A, Hemdani N, Ennaifer R, Bel Hadj Ammar L, Nsibi S, Tlili R, Kallel L, Hamida SB, Elloumi H, Cheikh I, Nouira M, Ennigrou S.   +72 more
europepmc   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

WeChat-based manual enhanced guidance in patients with Helicobacter pylori infection. [PDF]

BMC Gastroenterol
Shi X, Li Z, Tong Z, Ye C, Xu W, Li H, Qi X.   +6 more
europepmc   +1 more source

SYMBOLIC RESISTANCE OF ACEHNESE STUDENTS AGAINST NATIONAL NARCOTICS AGENCY HEGEMONY ON DRUG ERADICATION

, 2019
Mohd Herry Mohd Nasir, Muhaini Muhaini, Muhammad Mukhlis   +2 more
openalex   +2 more sources

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Gastric Cancer after <italic>Helicobacter pylori</italic> Eradication: Characteristics, Diagnosis, and Management. [PDF]

Digestion
Myeong S, Kim I, Kang D, Cho YK, Park JM.   +4 more
europepmc   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Alterations in the gut microbiota of Chinese patients following <i>Helicobacter pylori</i> eradication with bismuth-based quadruple therapy. [PDF]

Front Microbiol
Chen XJ, Hu MY, Zheng ED, Pan JY.
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source