Results 211 to 220 of about 38,315 (266)

Targeting erbB Pathways in Breast Cancer: Dual Kinase Inhibition for Brain Metastasis and Prevention of p185HER2/Neu Tumor Development. [PDF]

open access: yesBreast Cancer (Dove Med Press)
Goel PN   +9 more
europepmc   +1 more source

Mitochondria‑derived peptides: Promising microproteins in cardiovascular diseases (Review). [PDF]

open access: yesMol Med Rep
Ran Y   +8 more
europepmc   +1 more source

The ErbB receptors and their role in cancer progression

Experimental Cell Research, 2003
The involvement of the ErbB receptor tyrosine kinases in human cancer, as well as their essential role in a variety of physiological events during normal development, have motivated the interest in this receptor family. Approaches taken to block the activity of ErbB receptors in cancer cells have not only proven that they drive in vitro tumor cell ...
Gianluca Civenni   +2 more
openaire   +3 more sources

ErbB receptors and signaling pathways in cancer

Current Opinion in Cell Biology, 2009
The ErbB receptor tyrosine kinases play important roles in normal physiology and in cancer. Epidermal growth factor receptor (EGFR) and ErbB2 in particular are mutated in many epithelial tumors, and clinical studies suggest that they play roles in cancer development and progression.
Gwen MacDonald, Nancy E. Hynes
openaire   +2 more sources

Evolution and Functional Divergence of the ERBB Receptor Family

Pharmacogenomics, 2021
Aim: The ERBB gene family plays an important role in cell proliferation and differentiation, and aberrant activations could result in tumorigenesis, which makes this gene family an attractive drug target in the area of precision oncology. Materials & methods: Functional divergence analysis and conservation analysis were performed using ClustalW, MEGA7 ...
Shanshan Wu   +5 more
openaire   +2 more sources

The EGF/ErbB Receptor Family and Apoptosis

Growth Factors, 2002
The ErbB receptor family can activate a multitude of cell signaling pathways that involve many aspects of cellular function. The four members of the ErbB receptor family interact with diverse ligands and substrates, as well as with each other through cell surface heterodimerization.
Nita J. Maihle, Andrew J. Danielsen
openaire   +2 more sources

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